CAJ | 학술논문

血-眼屏障( blood-eye barrier,BEB)是机体维持眼内环境稳定的重要结构之一,但同时也是药物治疗内眼疾病的主要制约因素。传统中药能调节人体生理功能,且毒副作用较低,对治疗内眼疾病有独特的优势。本文结合国内外文献报道,对BEB的特性作简要概括,并重点综述中药及其有效成分在 BEB 通透性及促透作用的研究进展。
혈-안병장( blood-eye barrier,BEB)시궤체유지안내배경은정적중요결구지일,단동시야시약물치료내안질병적주요제약인소。전통중약능조절인체생리공능,차독부작용교저,대치료내안질병유독특적우세。본문결합국내외문헌보도,대BEB적특성작간요개괄,병중점종술중약급기유효성분재 BEB 통투성급촉투작용적연구진전。
Blood-eye barrier (BEB) is one of the most important structures of organism to maintain homeostasis of the eye. However, it is the major constraint for the medication of intraocular diseases. Traditional Chinese medicines have distinctive advantages for the treatment of intraocular diseases, which can be used to regulate the physiological function of human body with low toxicity. In this article, we have briefly summarized the feature of BEB, with the domestic and foreign literatures combined, and mainly reviewed current progress in the field of study on the permeability of traditional Chinese medicines and effective components in BEB and promoting methods.