CAJ | 학술논문

目的：对CT肺动脉造影与MR评估肺动脉栓塞（ PE）的临床应用价值进行Meta分析。方法网络检索中英文数据库MEDLINE、EMBASE、Cochrane图书馆、CBM、CNKI和万方数据等，搜集公开发表的关于CT肺动脉造影与肺动脉MR评估PE的文献，应用STATA12；．0统计软件进行数据合并，计算诊断试验的敏感性、特异性和ROC曲线下面积（ AUC）。结果共16项研究1497例受试对象纳入Meta分析，其中应用CT肺动脉造影评价PE 11项研究，MR检查5项研究。 Meta分析结果显示CT肺动脉造影和MR评价PE的敏感性分别为0．79（95％CI 0．75～0．83）和0．54（95％CI 0．48～0．60），特异性分别为0．90（95％CI 0．87～0．93）和0．98（95％CI 0．96～1．00）；CT肺动脉造影和MR评价PE的AUC分别为0．94（95％CI 0．92～0．96）和0．99（95％CI 0．97～0．99）。结论 CT肺动脉造影与MR评估PE的准确性较高，可作为临床评估PE的有效方法。
목적：대CT폐동맥조영여MR평고폐동맥전새（ PE）적림상응용개치진행Meta분석。방법망락검색중영문수거고MEDLINE、EMBASE、Cochrane도서관、CBM、CNKI화만방수거등，수집공개발표적관우CT폐동맥조영여폐동맥MR평고PE적문헌，응용STATA12；．0통계연건진행수거합병，계산진단시험적민감성、특이성화ROC곡선하면적（ AUC）。결과공16항연구1497례수시대상납입Meta분석，기중응용CT폐동맥조영평개PE 11항연구，MR검사5항연구。 Meta분석결과현시CT폐동맥조영화MR평개PE적민감성분별위0．79（95％CI 0．75～0．83）화0．54（95％CI 0．48～0．60），특이성분별위0．90（95％CI 0．87～0．93）화0．98（95％CI 0．96～1．00）；CT폐동맥조영화MR평개PE적AUC분별위0．94（95％CI 0．92～0．96）화0．99（95％CI 0．97～0．99）。결론 CT폐동맥조영여MR평고PE적준학성교고，가작위림상평고PE적유효방법。
Objective To investigate the CT and MR in the diagnosis of pulmonary embolism ( PE) by using evidence based medicine.Methods By searching MEDLINE, EMBSE, Cochrane library, CBM, CNKI and Wanfang dade et al , the prospective clinical trials of the of CT and MR in the diagnosis of pulmonary embolism ( PE) were included in the Meta-analy-sis,then use STATA12.0 software to combine the data,calculate the sensitivity,specificity and area under ROC(AUC).Re-sults 16 papers were recruited in the study with 1 497 cases, including 11 papers about CT pulmonary artery angiography and 5 papers about MR exam.The pooled sensitivity, specificity, and ROC curve were 0.79 (95%CI 0.75-0.83), 0.90 (95%CI 0.87-0.93) and 0.94 (95%CI 0.92-0.96) respectively for CT pulmonary artery angiography .And 0.54 (95%CI 0.48-0.60), 0.98 (95%CI 0.96-1.00) and 0.99 (95%CI 0.97-0.99) respectively for MR.Conclusion CT pulmo-nary artery angiography and MR were relative high in the diagnosis of PE ,which can be a useful tool for non-invasive diagnosis .