中国保健营养（中旬刊）
中國保健營養（中旬刊）
중국보건영양（중순간）
China Hwalth Care & nutrition
2013年
8期
15-15
,共1页
阿伐他汀%急性心肌梗死%溶栓%心肌保护
阿伐他汀%急性心肌梗死%溶栓%心肌保護
아벌타정%급성심기경사%용전%심기보호
Myocardial%Acute myocardial infarction%Thrombolysis%Myocardial preservation
目的：探讨大量阿伐他汀在急性心肌梗死溶栓治疗后心肌保护作用。方法：选择我院在2010年2月至2012年5月收治的80例采用溶栓治疗的急性心肌梗死患者，分别给予大剂量阿伐他汀（观察组，n =40）或常规剂量阿伐他汀（对照组，n =40），然后分析两组患者的 CK-MB、cTnⅠ、sVCAM-1、sICAM-1以及 BNP 变化。结果：溶栓后24小时观察组患者的 CK-MB、cTnⅠ、sVCAM-1和 sICAM-1水平均显著地低于对照患者。溶栓治疗1个月后观察组患者的 cTnⅠ、sVCAM-1、sICAM-1以及 BNP 水平明显低于对照组患者。并且观察组患者的溶栓后2小时心律失常发生率以及治疗后6个月内的心血管事件发生率都显著小于对照组患者。结论：大量阿伐他汀在急性心肌梗死溶栓治疗后保护心肌作用更明显，有利于患者的预后，值得临床推广。
目的：探討大量阿伐他汀在急性心肌梗死溶栓治療後心肌保護作用。方法：選擇我院在2010年2月至2012年5月收治的80例採用溶栓治療的急性心肌梗死患者，分彆給予大劑量阿伐他汀（觀察組，n =40）或常規劑量阿伐他汀（對照組，n =40），然後分析兩組患者的 CK-MB、cTnⅠ、sVCAM-1、sICAM-1以及 BNP 變化。結果：溶栓後24小時觀察組患者的 CK-MB、cTnⅠ、sVCAM-1和 sICAM-1水平均顯著地低于對照患者。溶栓治療1箇月後觀察組患者的 cTnⅠ、sVCAM-1、sICAM-1以及 BNP 水平明顯低于對照組患者。併且觀察組患者的溶栓後2小時心律失常髮生率以及治療後6箇月內的心血管事件髮生率都顯著小于對照組患者。結論：大量阿伐他汀在急性心肌梗死溶栓治療後保護心肌作用更明顯，有利于患者的預後，值得臨床推廣。
목적：탐토대량아벌타정재급성심기경사용전치료후심기보호작용。방법：선택아원재2010년2월지2012년5월수치적80례채용용전치료적급성심기경사환자，분별급여대제량아벌타정（관찰조，n =40）혹상규제량아벌타정（대조조，n =40），연후분석량조환자적 CK-MB、cTnⅠ、sVCAM-1、sICAM-1이급 BNP 변화。결과：용전후24소시관찰조환자적 CK-MB、cTnⅠ、sVCAM-1화 sICAM-1수평균현저지저우대조환자。용전치료1개월후관찰조환자적 cTnⅠ、sVCAM-1、sICAM-1이급 BNP 수평명현저우대조조환자。병차관찰조환자적용전후2소시심률실상발생솔이급치료후6개월내적심혈관사건발생솔도현저소우대조조환자。결론：대량아벌타정재급성심기경사용전치료후보호심기작용경명현，유리우환자적예후，치득림상추엄。
Objective: To explore the role of high dose of atorvastatin on myocardial preservation of acute myocardial infarction after thrombolysis treatment. Methods:Analyzed the CK-MB, cTnⅠ, sVCAM-1, sICAM-1 and BNP changes of the high dose of atorvastatin (Observation group, n = 40) or low dose of atorvastatin (Control group, n = 40) for treatment of 80 newborn patients with acute myocardial infarction after thrombolysis treatmentin our hospital from February 2010 to May 2012. Results: 24 hours after thrombolysis treatment the CK-MB, cTnⅠ, sVCAM-1, and sICAM-1 in the observation group were significantly lower than those in the control group. 1 month after thrombolysis treatment the cTnⅠ, sVCAM-1, sICAM-1, and BNP in the observation group were significantly lower than those in the control group. Moreover, the arrhythmia rate 2 hours after thrombolysis and cardiac events rate between 6 months after treatment in the observation group were significantly lower than those in the control group. Conclusions: High dose of atorvastatin on myocardial preservation acute myocardial infarction after thrombolysis treatment has more significant role. It is worthy to be popularized.
