CAJ | 학술논문

目的：观察坎地沙坦对VD患者hs-CRP的影响。方法选择2011.2～2013.11我科收治的VD患者40例，分为坎地沙坦治疗组（即治疗组）20例和对照组20例，其中治疗组男12例，女8例；对照组男11例，女9例，两组均给予阿司匹林、尼莫地平及相同的活血化瘀药物等常规治疗及对症处理，治疗组在此基础上给予口服坎地沙坦片，治疗前及治疗后4W行hs-CRP检测。结果4W后，治疗组较对照组患者的hs-CRP水平显著降低（P<0.05）。结论坎地沙坦联合阿司匹林、尼莫地平等常规药物可抑制血管性痴呆患者的微炎症反应，无明显不良反应，临床中值得应用。
목적：관찰감지사탄대VD환자hs-CRP적영향。방법선택2011.2～2013.11아과수치적VD환자40례，분위감지사탄치료조（즉치료조）20례화대조조20례，기중치료조남12례，녀8례；대조조남11례，녀9례，량조균급여아사필림、니막지평급상동적활혈화어약물등상규치료급대증처리，치료조재차기출상급여구복감지사탄편，치료전급치료후4W행hs-CRP검측。결과4W후，치료조교대조조환자적hs-CRP수평현저강저（P<0.05）。결론감지사탄연합아사필림、니막지평등상규약물가억제혈관성치태환자적미염증반응，무명현불량반응，림상중치득응용。
Objective Observation on the effect of candesartan on VD in patients with hs-CRP. Methods Choose 2011.2 to 2013.11 in our hospital from 40 VD patients, divided into candesartan treatment group (treatment group) 20 cases and control group 20 cases, the treatment group male 12 cases, female 8 cases; control group, male 11 cases, female 9 cases, the two groups were given aspirin, nimodipine and the same the Huoxue Huayu drugs and other conventional treatment and symptomatic treatment, the treatment group based on the given oral candesartan cilexetil tablets, before and after treatment with 4W for hs-CRP detection. Results After 4W, the treatment group was significantly lower than that of control group (P<0.05) level in patients with hs-CRP.Conclusion The micro inflammatory reaction of candesartan in combination with aspirin, nimodipine and other conventional drugs can inhibit vascular dementia patients, no significant adverse reactions, is worthy of clinical application.