CAJ | 학술논문

目的：调查本院门诊镇静催眠药的使用情况,促进临床合理用药。方法：对门诊1393张镇静催眠药处方的资料进行统计,分析其在是否联用、使用频率、药物利用指数( DUI)、用药诊断、用药时间等方面的临床分布特点。结果：本院镇静催眠药基本上以单用为主,占96.41%,药物品种主要是苯二氮类,占95.3%,其中以阿普唑仑最为常见,占26.74%,统计药物的DUI值大体都符合规定(DUI≤1)；主要用于精神分裂症(47.81%)及心境障碍(17.09%)；时间<4周684例(47.27%),4周~2个月488例(33.72%),2个月~4个月271例(18.73%),>4个月4例(0.28%)。结论：本院镇静催眠药物的使用基本合理,但仍存在持续使用时间偏长的问题,应引起医生、药师及患者重视,防止药物的滥用及依赖性的发生。
목적：조사본원문진진정최면약적사용정황,촉진림상합리용약。방법：대문진1393장진정최면약처방적자료진행통계,분석기재시부련용、사용빈솔、약물이용지수( DUI)、용약진단、용약시간등방면적림상분포특점。결과：본원진정최면약기본상이단용위주,점96.41%,약물품충주요시분이담류,점95.3%,기중이아보서륜최위상견,점26.74%,통계약물적DUI치대체도부합규정(DUI≤1)；주요용우정신분렬증(47.81%)급심경장애(17.09%)；시간<4주684례(47.27%),4주~2개월488례(33.72%),2개월~4개월271례(18.73%),>4개월4례(0.28%)。결론：본원진정최면약물적사용기본합리,단잉존재지속사용시간편장적문제,응인기의생、약사급환자중시,방지약물적람용급의뢰성적발생。
Objective:To investigates applications of sedative hypnotic drugs in outpatient department of our hospital so as to promote clinical rational drug use. Methods:1393 outpatient prescriptions of the sedative hypnotic drugs in April 2013 were statistical-ly analyzed to explore the clinical distribution characteristics like combination or not, use frequency, drug utilization index (DUI), clinical diagnosis, medication time. Results: In our hospital, the sedative hypnotics was basically used singly, accounting for 96. 41%. The drug used was mainly BDZs, accounting for 95. 3%, of which alprazolam was the most common, accounting for 26. 74%. DUI value of the drugs statistics was generally consistent with the regulation (DUI≤1). These drugs were mainly used for schizophrenia (47. 81%) and mood disorders (17. 09%). The medication time was less than 4 weeks for 684 cases (47. 27%), 4 weeks-2 months for 488 cases (33. 72%), 2- 4 months for 271 18. 73%), and greater than 4 months for 4 cases (0. 28%). Con-clusions:The sedative hypnotic drugs using in our hospital are basically reasonable, however, there exists the problem that the medica-tion time for continuously using the drug is quite long. The attention should be paid to by the doctors, pharmacists and patients in order to prevent the occurrence of drug abuse and dependence.