CAJ | 학술논문

目的：观察2型糖尿病合并非ST段抬高急性冠脉综合征(NSTE-ACS)患者糖化血红蛋白(HbA1c)水平与全球急性冠脉事件注册(GRACE)危险评分的相关性。方法67例非ST段抬高急性冠脉综合征合并糖尿病均行经冠状动脉造影确诊，同时选择单纯NSTE-ACS患者67例作为对照组。测定HbA1c水平，比较NSTE-ACS合并2型糖尿病患者GRACE危险评分与 HbA1c水平相关性。结果血清HbA1c水平与GRACE危险评分呈正相关，高危组患者的血清 HbA1c水平明显高于中、低危组，高血清HbA1c水平NSTE-ACS患者的GRACE危险评分也高于低血清HbA1c水平患者，差异均有统计学意义(P<0.01)。结论血清 HbA1c水平对NSTE-ACS合并2型糖尿病患者预后评估与GRACE危险评分具有临床一致性。
목적：관찰2형당뇨병합병비ST단태고급성관맥종합정(NSTE-ACS)환자당화혈홍단백(HbA1c)수평여전구급성관맥사건주책(GRACE)위험평분적상관성。방법67례비ST단태고급성관맥종합정합병당뇨병균행경관상동맥조영학진，동시선택단순NSTE-ACS환자67례작위대조조。측정HbA1c수평，비교NSTE-ACS합병2형당뇨병환자GRACE위험평분여 HbA1c수평상관성。결과혈청HbA1c수평여GRACE위험평분정정상관，고위조환자적혈청 HbA1c수평명현고우중、저위조，고혈청HbA1c수평NSTE-ACS환자적GRACE위험평분야고우저혈청HbA1c수평환자，차이균유통계학의의(P<0.01)。결론혈청 HbA1c수평대NSTE-ACS합병2형당뇨병환자예후평고여GRACE위험평분구유림상일치성。
Objective To investigate correlation of serum level of HbA1c and GRACE risk score in patients with non-ST segment elevation acute coronary syndrome (NSTE-ACS) and type 2 diabetes. Methods All of 134 patients undergoing coronary angiography(CAG), 67 patients were diagnosed with type 2 diabetes and NSTE-ACS, the other 67 patients with NSTE-ACS cases were served as control. The serum level of HbA1c was measured in peripheral venous blood by in all the patients, and the GRACE risk score were assessed in patients with type 2 diabetes. The serum level of HbA1c and GRACE risk score were analyzed by Spearman rank correlation. Results The serum level of HbA1c was significantly higher in patients with Type 2 diabetes and NSTE-ACS than the control (all P<0.01). The serum level of HbA1c in patients with NSTE-ACS were positively correlated with GRACE risk score (r=0.503, P=0.001). Conclusion The serum level of HbA1c has a good consistency with GRACE risk score in NSTE-ACS patients with type 2 diabetes.