CAJ | 학술논문

目的：探讨心力衰竭患者利尿治疗前后aVR导联QRS波振幅与脑钠肽变化的关系，探讨心力衰竭治疗有效的心电图指标，为临床疗效评估提供简便易行的预测方法。方法观察心力衰竭患者50例，分别于入院时利尿治疗前及治疗后出院时行12导联心电图检查，观察aVR导联QRS波振幅变化；监测体重；测定脑钠肽浓度。结果心力衰竭患者经利尿治疗后心电图aVR导联QRS波的振幅较治疗前显著增高，体重显著下降，BNP显著下降。结论 aVR导联QRS波振幅变化与脑钠肽可以用来评估心力衰竭患者利尿治疗疗效的简单可靠的指标。
목적：탐토심력쇠갈환자이뇨치료전후aVR도련QRS파진폭여뇌납태변화적관계，탐토심력쇠갈치료유효적심전도지표，위림상료효평고제공간편역행적예측방법。방법관찰심력쇠갈환자50례，분별우입원시이뇨치료전급치료후출원시행12도련심전도검사，관찰aVR도련QRS파진폭변화；감측체중；측정뇌납태농도。결과심력쇠갈환자경이뇨치료후심전도aVR도련QRS파적진폭교치료전현저증고，체중현저하강，BNP현저하강。결론 aVR도련QRS파진폭변화여뇌납태가이용래평고심력쇠갈환자이뇨치료료효적간단가고적지표。
Objective To explore the changes of QRS-wave amplitude in aVR lead and brain natriuretic peptide(BNP) before and after the diuretic therapy for patients with heart failure, and to explore the effective indices of ECG for the treatment of heart failure, so as to provide easy predictions for the evaluation of clinical curative effects. Methods 50 patients with heart failure were observed and received 12-lead ECG before the diuretic therapy on admission and after the therapy on discharge. Changes of QRS-wave amplitude in aVR lead were observed; patients' weights were monitored; concentrations of BNP were tested. Results The QRS-wave amplitude in aVR lead for patients with heart failure after the diuretic therapy was significantly higher than that before the therapy. Patients' weights and BNP concentrations significantly reduced. Conclusion Changes of QRS-wave amplitude in aVR lead and BNP can be used as easy and reliable indices for the evaluation of curative effects of diuretic therapy for patients with heart failure.