CAJ | 학술논문

目的：观察米诺环素治疗老年医院获得性肺炎的疗效及不良反应。方法收集医院获得性肺炎老年患者56例，随机分成两组，米诺环素联合头孢哌酮钠舒巴坦钠组和头孢哌酮钠舒巴坦钠组，采用统计学方法进行疗效分析。结果联合用药组和头孢哌酮钠舒巴坦钠组治疗老年医院获得性肺炎的总有效率分别为85.71%和71.43%，联合用药组治疗效果较好，组间比较具有统计学差异( P<0.05)。结论与单用头孢哌酮钠舒巴坦钠相比，米诺环素与头孢哌酮钠舒巴坦钠联合用药治疗老年医院获得性肺炎的效果更理想。
목적：관찰미낙배소치료노년의원획득성폐염적료효급불량반응。방법수집의원획득성폐염노년환자56례，수궤분성량조，미낙배소연합두포고동납서파탄납조화두포고동납서파탄납조，채용통계학방법진행료효분석。결과연합용약조화두포고동납서파탄납조치료노년의원획득성폐염적총유효솔분별위85.71%화71.43%，연합용약조치료효과교호，조간비교구유통계학차이( P<0.05)。결론여단용두포고동납서파탄납상비，미낙배소여두포고동납서파탄납연합용약치료노년의원획득성폐염적효과경이상。
Objective To investigate the clinical efficacy and adverse reactions of minocycline for treating senile hospital acquired pneu-monia ( HAP ) in order to provide reference for clinical medication. Methods 56 senile cases of HAP in our hospital were collected and randomly divided into 2 groups. The two groups were treated with sulbactam sodium and cefoperazone sodium and minocycline combined with sulbactam sodium and cefoperazone sodium, respectively. The effects were analyzed and compared between the two groups by the statistical method. Resuts The effective rates of the sulbactam sodium and cefoperazone sodium group and the combined medication group were 85. 71% and 71. 43% respectively. The combined medication group had better curative effect, the difference between the two groups had statistical significance ( P<0. 05 ) . Conclusion Minocycline combined with sulbactam sodium and cefoperazone sodium has the ideal effect in the treatment of senile HAP compared with simple sulbactam sodium and cefoperazone sodium.