CAJ | 학술논문

目的：观察注射用头孢唑林钠与丹皮酚磺酸钠注射液在0.9%氯化钠注射液中的配伍稳定性。方法模拟临床使用条件，用高效液相色谱法测定头孢唑林钠与丹皮酚磺酸钠配伍后6 h内的相对百分含量，并观察其外观、不溶性微粒数及pH变化。结果头孢唑林钠与丹皮酚磺酸钠配伍后，在室温下放置6 h，配伍液的外观、不溶性微粒数、pH及含量均无明显变化。结论注射用头孢唑林钠与丹皮酚磺酸钠注射液在0.9%氯化钠注射液中配伍后，室温下6 h内可使用。
목적：관찰주사용두포서림납여단피분광산납주사액재0.9%록화납주사액중적배오은정성。방법모의림상사용조건，용고효액상색보법측정두포서림납여단피분광산납배오후6 h내적상대백분함량，병관찰기외관、불용성미립수급pH변화。결과두포서림납여단피분광산납배오후，재실온하방치6 h，배오액적외관、불용성미립수、pH급함량균무명현변화。결론주사용두포서림납여단피분광산납주사액재0.9%록화납주사액중배오후，실온하6 h내가사용。
Objective To study the compatible stability of Cefazolin Sodium Injection with Sodium Paeonol Sulfonate Injection in 0. 9%Sodium Chloride Injection. Methods The high performance liquid chromatography ( HPLC ) was adopted to detect the relative percentage content of cefazolin sodium and sodium paeonol sulfonate within 6 h in stimulated clinical conditions. The appearance of the solution, pH value and the number of insoluble particles were observed. Results There were no evident changes in the appearance, pH value, number of insoluble particles and the content of cefazolin sodium and sodium paeonol sulfonate of the compatible solution within 6 h at room temperature. Conclusion The compatible solution of Cefazolin Sodium Injection with Sodium Paeonol Sulfonate Injection in 0. 9%Sodium Chloride Injection can be used within 6 h at room temperature .