CAJ | 학술논문

目的：探究cTnT、NT-proBNP及心肌酶谱联合检测诊治急性冠脉综合征（ ACS）中的临床意义。方法选取该院2012年1月至2013年5月所收治的收治并确诊急性冠脉综合征患者24例，作为观察组，同时，针对该院在同期间入住的24例主要临床表现为“胸闷，难受，呼吸困难，胸痛”的患者为对照组，对患者的血样进行肌钙蛋白（ cTnT ）、N-端脑钠肽前体（ NT-proBNP ）、天门冬氨酸转移酶（ AST）、肌酸激酶（ CK）、乳酸脱氢酶（ LDH）及肌酸激酶同工酶（ CK-MB）的含量进行测定。结果治疗前，观察组在急性冠脉综合征患者各个指标均高于对照组，并且数据间差别存在显著性，即P＜0．05。治疗后，观察组中急性冠脉综合征患者在CTnT、NT-proBNP均高于对照组，并且数据间差别存在显著性，即P＜0．05，而两组在CK、CK-MB、LDH和AST上与对照组相比，无统计学差异（ P＞0．05）。结论 cTnT、NT-proBNP及心肌酶谱的检测对急性冠脉综合征患者的应用价值较高，可以有效反映ACS的具体情况，对ACS 的早期诊断及治疗具有非常重要的价值。
목적：탐구cTnT、NT-proBNP급심기매보연합검측진치급성관맥종합정（ ACS）중적림상의의。방법선취해원2012년1월지2013년5월소수치적수치병학진급성관맥종합정환자24례，작위관찰조，동시，침대해원재동기간입주적24례주요림상표현위“흉민，난수，호흡곤난，흉통”적환자위대조조，대환자적혈양진행기개단백（ cTnT ）、N-단뇌납태전체（ NT-proBNP ）、천문동안산전이매（ AST）、기산격매（ CK）、유산탈경매（ LDH）급기산격매동공매（ CK-MB）적함량진행측정。결과치료전，관찰조재급성관맥종합정환자각개지표균고우대조조，병차수거간차별존재현저성，즉P＜0．05。치료후，관찰조중급성관맥종합정환자재CTnT、NT-proBNP균고우대조조，병차수거간차별존재현저성，즉P＜0．05，이량조재CK、CK-MB、LDH화AST상여대조조상비，무통계학차이（ P＞0．05）。결론 cTnT、NT-proBNP급심기매보적검측대급성관맥종합정환자적응용개치교고，가이유효반영ACS적구체정황，대ACS 적조기진단급치료구유비상중요적개치。
Objective To investigate the clinical Value of Troponin T ,N-terminal pro-B-type natriuretic peptide and myocardial enzyme spectrum in diagnosis of acute coronary syndrome .Methods 24 patients with acute coronary syndrome were selected from Janurary 2012 to May 2013 in our hospital as the observation group .Meanwhile,for the same period of stay in the hospital main clinical manifes-tations,24 cases of patients with "chest tightness,discomfort,difficulty breathing,chest pain"was the control group.The levels of cTnT, NT-proBNP,AST,CK,LDH and CK-MB were determined .Results Before treatment ,the observation group were higher in patients with acute coronary syndromes various indicators was significantly higher ,and there is a significant difference between the data (P<0.05). After treatment ,Observed group of patients with acute coronary syndrome in calcium protein T , serum brain natriuretic peptide were higher,and there is a significant difference between the data ,that is P<0.05,while the two groups in creatine kinase ,creatine kinase isoforms enzyme,lactate dehydrogenase and aspartate shift compared with the control group was no significant difference (P>0.05) on the enzyme.Conclusion cTnT,NT-proBNP and detection of myocardial enzymes value is higher in patients with acute coronary syn -drome and it can effectively reflect the specific circumstances of the ACS ,so it has a very important value for the early diagnosis and treatment of ACS .