CAJ | 학술논문

目的：了解食管癌高发区居民食管癌及癌前病变的患病情况。方法：在四川省巴中市食管癌高发区，采取整群随机抽样的方法选择部分自然村，以40~69岁居民作为筛查对象，进行内镜下碘染色及指示性活检筛查，并经病理学最终诊断确诊。结果：食管炎症及食管轻、中、重度异型增生的检出率分别为7.81%(513/6571)、5.63%(370/6571)、1.99%(131/6571)、0.79%(52/6571)，食管癌的检出率为0.21%(14/6571)；各个级别食管病变的检出率男性均高于女性；各年龄段分析发现，各级别食管病变检出率在不同年龄组之间的构成差异有统计学意义(P<0.05)；结合年龄分布图发现，居民食管炎症、轻度食管异型增生、中度食管异型增生的检出率有随着年龄的增长而增加的趋势。结论：应在食管癌高发区继续推广癌症早诊早治工作，做到食管癌的早发现、早诊断、早治疗。
목적：료해식관암고발구거민식관암급암전병변적환병정황。방법：재사천성파중시식관암고발구，채취정군수궤추양적방법선택부분자연촌，이40~69세거민작위사사대상，진행내경하전염색급지시성활검사사，병경병이학최종진단학진。결과：식관염증급식관경、중、중도이형증생적검출솔분별위7.81%(513/6571)、5.63%(370/6571)、1.99%(131/6571)、0.79%(52/6571)，식관암적검출솔위0.21%(14/6571)；각개급별식관병변적검출솔남성균고우녀성；각년령단분석발현，각급별식관병변검출솔재불동년령조지간적구성차이유통계학의의(P<0.05)；결합년령분포도발현，거민식관염증、경도식관이형증생、중도식관이형증생적검출솔유수착년령적증장이증가적추세。결론：응재식관암고발구계속추엄암증조진조치공작，주도식관암적조발현、조진단、조치료。
[ Abstract] Objective: To explore the prevalence of esophageal cancer and precancerous lesions of esophagus in high risk areas. Methods:A portion of natural villages in the high risk areas of esophageal cancer was selected by random cluster sampling method and people aged 40 to 69 years were chosen as the screening objects . Endoscope assisted iodine staining and indicative biopsy screening were adopted. The final results were confirmed by pathological diagnosis. Results:The detecting rate of esophagus inflammation, mild, moderate, severe esophageal hyperplasia and esophageal cancer was 7. 81%(513/6 571), 5. 63%(370/6 571), 1. 99%(131/6 571), 0. 79%(52/6 571),and 0. 21%(14/6 571)respective-ly. The detecting rates of esophageal lesions at various grades in males were higher than those of females. The analysis de-pending on different age scopes found that the composition of the detecting rate of each grade of esophageal lesion between different age groups was significantly different (P<0. 05). Combined with the age distribution figure, the detecting rate of esophageal inflammation, mild and moderate hyperplasia showed an increasing tendency with age. Conclusion:Early diag-nosis and treatment should be promoted constantly in high risk area of esophageal cancer , thus the early finding, diagnosis and control work of esophageal cancer can be achieved.