CAJ | 학술논문

目的：评价复方倍他米松注射液皮损内注射联合5％咪喹莫特乳膏外涂治疗瘢痕疙瘩的疗效。方法：将患者随机分为两组，治疗组给予复方倍他米松注射液皮损内注射，每3周1次，共3次。同时给予隔日外涂5％咪喹莫特乳膏，连续3个月；对照组单纯给予复方倍他米松注射液皮损内注射。两组患者均于疗程结束后6个月评价疗效和复发。结果：治疗组有效率93.55％，对照组有效率70.37％，复发率治疗组低于对照组，差异有显著性意义，不良反应轻微。结论：复方倍他米松注射液皮损内注射联合5％咪喹莫特乳膏外涂治疗瘢痕疙瘩安全、有效。
목적：평개복방배타미송주사액피손내주사연합5％미규막특유고외도치료반흔흘탑적료효。방법：장환자수궤분위량조，치료조급여복방배타미송주사액피손내주사，매3주1차，공3차。동시급여격일외도5％미규막특유고，련속3개월；대조조단순급여복방배타미송주사액피손내주사。량조환자균우료정결속후6개월평개료효화복발。결과：치료조유효솔93.55％，대조조유효솔70.37％，복발솔치료조저우대조조，차이유현저성의의，불량반응경미。결론：복방배타미송주사액피손내주사연합5％미규막특유고외도치료반흔흘탑안전、유효。
Objective: To assess the therapeutic efficacy of compound betamethasone injection combined with local injection with 5% imiquimod cream in the treatment of keloid. Methods:The patients were random-ly divided into two groups. The treatment group was given intralesional compound betamethasone, once every 3 weeks for 3 times, combined with topical daily 5% imiquimod cream for 3 months. The control group only re-ceived compound betamethasone intralesional injection. The clinical efficacy and side effects were assessed af-ter 6 months. Results:The effective rates in the treatment and control group were 93.55% and 70.37%, re-spectively, with a significant difference. The recurrence rate was lower in the treatment group than in the con-trol group, with a significant difference. The side effects were mild. Conclusion:Compound betamethasone in-jection combined with 5% imiquimod cream is safe and effective in the treatment of keloid.