中国组织工程研究
中國組織工程研究
중국조직공정연구
Journal of Clinical Rehabilitative Tissue Engineering Research
2014年
13期
2077-2082
,共6页
植入物%脊柱植入物%组织工程骨材料%椎体成形术%腰椎%骨质疏松%压缩骨折%骨水泥%椎体裂隙%胸椎
植入物%脊柱植入物%組織工程骨材料%椎體成形術%腰椎%骨質疏鬆%壓縮骨摺%骨水泥%椎體裂隙%胸椎
식입물%척주식입물%조직공정골재료%추체성형술%요추%골질소송%압축골절%골수니%추체렬극%흉추
biocompatible materials%vertebroplasty%osteoporosis%fractures,bone
背景：临床实践证明经皮椎体成形治疗骨质疏松性椎体压缩骨折有显著的疗效。<br> 目的：比较经皮椎体成形治疗伴或不伴椎体内裂隙样变骨质疏松性椎体压缩骨折的治疗效果，以确定椎体成形治疗椎体裂隙样变骨质疏松性椎体压缩骨折的有效性和安全性。<br> 方法：选择骨质疏松性椎体压缩骨折患者76例，分两组，实验组27例伴椎体内裂隙样变，对照组49例不伴椎体内裂隙样变。采用椎体成形治疗后，比较两组间目测类比评分和Oswesty功能障碍指数值、椎体前缘高度的变化，以及发生骨水泥外漏的类型和特点。<br> 结果与结论：两组治疗后的目测类比评分、Oswesty功能障碍指数值均明显低于治疗前(P<0.05)，治疗后两组间目测类比评分、Oswesty功能障碍指数值及骨水泥外漏发生率比较差异无显著性意义(P>0.05)。两组治疗后的伤椎高度与治疗前比较差异无显著性意义(P>0.05)。说明椎体成形是减轻伴或不伴有椎体裂隙骨质疏松性椎体压缩骨折患者疼痛，改善脊柱活动功能及提高患者社会活动能力的有效方法，但不能有效恢复椎体高度。
揹景：臨床實踐證明經皮椎體成形治療骨質疏鬆性椎體壓縮骨摺有顯著的療效。<br> 目的：比較經皮椎體成形治療伴或不伴椎體內裂隙樣變骨質疏鬆性椎體壓縮骨摺的治療效果，以確定椎體成形治療椎體裂隙樣變骨質疏鬆性椎體壓縮骨摺的有效性和安全性。<br> 方法：選擇骨質疏鬆性椎體壓縮骨摺患者76例，分兩組，實驗組27例伴椎體內裂隙樣變，對照組49例不伴椎體內裂隙樣變。採用椎體成形治療後，比較兩組間目測類比評分和Oswesty功能障礙指數值、椎體前緣高度的變化，以及髮生骨水泥外漏的類型和特點。<br> 結果與結論：兩組治療後的目測類比評分、Oswesty功能障礙指數值均明顯低于治療前(P<0.05)，治療後兩組間目測類比評分、Oswesty功能障礙指數值及骨水泥外漏髮生率比較差異無顯著性意義(P>0.05)。兩組治療後的傷椎高度與治療前比較差異無顯著性意義(P>0.05)。說明椎體成形是減輕伴或不伴有椎體裂隙骨質疏鬆性椎體壓縮骨摺患者疼痛，改善脊柱活動功能及提高患者社會活動能力的有效方法，但不能有效恢複椎體高度。
배경：림상실천증명경피추체성형치료골질소송성추체압축골절유현저적료효。<br> 목적：비교경피추체성형치료반혹불반추체내렬극양변골질소송성추체압축골절적치료효과，이학정추체성형치료추체렬극양변골질소송성추체압축골절적유효성화안전성。<br> 방법：선택골질소송성추체압축골절환자76례，분량조，실험조27례반추체내렬극양변，대조조49례불반추체내렬극양변。채용추체성형치료후，비교량조간목측류비평분화Oswesty공능장애지수치、추체전연고도적변화，이급발생골수니외루적류형화특점。<br> 결과여결론：량조치료후적목측류비평분、Oswesty공능장애지수치균명현저우치료전(P<0.05)，치료후량조간목측류비평분、Oswesty공능장애지수치급골수니외루발생솔비교차이무현저성의의(P>0.05)。량조치료후적상추고도여치료전비교차이무현저성의의(P>0.05)。설명추체성형시감경반혹불반유추체렬극골질소송성추체압축골절환자동통，개선척주활동공능급제고환자사회활동능력적유효방법，단불능유효회복추체고도。
BACKGROUND:Clinical practice verified that percutaneous vertebroplasty in the treatment of osteoporotic vertebral compression fractures obtained obvious curative effects. <br> OBJECTIVE:To compare the therapeutic effect of percutaneous vertebroplasty for treatment for osteoporotic vertebral compression fractures with or without intravertebral cleft, in order to evaluate the efficacy and safety of percutaneous vertebroplasty for treatment of osteoporotic vertebral compression fractures. <br> METHODS:A total of 76 patients with osteoporotic vertebral compression fractures were selected and divided into two groups. Experimental group consisted of 27 patients with intravertebral cleft. Control group comprised 49 patients without intravertebral cleft. After vertebroplasty, visual analogue scale and Oswestry disability index, changes of anterior vertebral height, and types and characteristics of bone cement leakage were compared between the two groups. <br> RESULTS AND CONCLUSION:Visual analogue scale and Oswestry disability index were significantly decreased after treatment in the two groups (P<0.05). No significant differences in visual analogue scale, Oswestry disability index and incidence of bone cement leakage were detected between the two groups after treatment (P>0.05). No significant difference in the height of injured vertebra was detectable between pretreatment and posttreatment in the two groups (P>0.05). These results suggested that vertebroplasty is an effective method for lessening the pain in osteoporotic vertebral compression fractures in patients with or without intravertebral cleft, improving spinal activity function and elevating social activities. However, percutaneous vertebroplasty cannot effectively recover the height of the vertebra.
