CAJ | 학술논문

目的：观察腹膜后精索静脉高位结扎术联合药物治疗精索静脉曲张（ VC）所致不育的临床疗效。方法将106例VC所致不育患者随机分为2组，治疗组55例应用腹膜后精索静脉高位结扎术联合药物治疗，对照组51例单纯应用腹膜后精索静脉高位结扎术治疗。观察2组术后3、6、9、12个月精液参数，术后随访3～24个月观察配偶妊娠率。结果2组手术后精液参数均较本组手术前提高（ P＜0．05）；治疗组手术后6个月精液参数较本组手术后3个月提高（P＜0．05）；治疗组手术后6、9、12个月精液参数比较差异无统计学意义（P＞0．05）；对照组手术后9个月精液参数较本组手术后6个月提高（P＜0．05）；对照组手术后9、12个月精液参数比较差异无统计学意义（P＞0．05）。治疗组手术后6个月精液参数较对照组同期提高（P＜0．01）。治疗组配偶妊娠率高于对照组（P＜0．01）。结论 VC所致不育患者腹膜后精索静脉高位结扎术联合药物治疗较单纯腹膜后精索静脉高位结扎术治疗能更明显、更快速地改善精液质量和提高配偶妊娠率。
목적：관찰복막후정색정맥고위결찰술연합약물치료정색정맥곡장（ VC）소치불육적림상료효。방법장106례VC소치불육환자수궤분위2조，치료조55례응용복막후정색정맥고위결찰술연합약물치료，대조조51례단순응용복막후정색정맥고위결찰술치료。관찰2조술후3、6、9、12개월정액삼수，술후수방3～24개월관찰배우임신솔。결과2조수술후정액삼수균교본조수술전제고（ P＜0．05）；치료조수술후6개월정액삼수교본조수술후3개월제고（P＜0．05）；치료조수술후6、9、12개월정액삼수비교차이무통계학의의（P＞0．05）；대조조수술후9개월정액삼수교본조수술후6개월제고（P＜0．05）；대조조수술후9、12개월정액삼수비교차이무통계학의의（P＞0．05）。치료조수술후6개월정액삼수교대조조동기제고（P＜0．01）。치료조배우임신솔고우대조조（P＜0．01）。결론 VC소치불육환자복막후정색정맥고위결찰술연합약물치료교단순복막후정색정맥고위결찰술치료능경명현、경쾌속지개선정액질량화제고배우임신솔。
Objective To observe the clinical effect of retroperitoneal varicocele high ligation combined with drug treatment on varicocele -caused infertility .Methods 106 infertility patients caused by varicocele were ran-domly divided into two groups .55 cases in treatment group were treated by retroperitoneal varicocele high ligation combined with drug treatment .51 cases in control group received only retroperitoneal varicocele high ligation .The se-men quality and enhance spouse pregnancy were observed in two groups at 3,6,9,12,18 months after surgery.The spouse pregnancy were recorded post -operation follow-up of 3-24 months.Results The seminal parameter post-operation were enhanced as compared with those before operation in two groups (P<0.05).The seminal parameter at six months post-operation were enhanced as compared with those at three months post operation in treatment group (P<0.05).There was no difference between the seminal parameters at six ,nine and twelve months post -operation in treatment group (P>0.05).The seminal parameter at nine months post -operation were enhanced as compared with those at six months post operation in control group (P<0.05).There was no difference between the seminal pa-rameters at nine and twelve months post -operation in control group (P>0.05).The seminal parameter in treatment group at six months post -operation were enhanced as compared with those in control group (P<0.01).The im-provement of the spouse pregnancy in treatment group was superior to that in control group ( P<0 .01 ) .Conclusion Retroperitoneal varicocele high ligation combined with drug treatment can more effectively and rapidly improve se -men qualityand enhance spouse pregnancy .