中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2014年
18期
68-70
,共3页
生长抑素%老年急性糜烂出血性胃炎%大出血
生長抑素%老年急性糜爛齣血性胃炎%大齣血
생장억소%노년급성미란출혈성위염%대출혈
Somatostatin%Acute erosive hemorrhagic gastritis in the elderly%Massive hemorrhage
目的：探讨生长抑素辅助治疗老年急性糜烂出血性胃炎大出血的临床效果。方法收集2012年8月~2013年8月本院消化内科收治的急性糜烂出血性胃炎老年患者32例，按照随机原则将其分为观察组和对照组各16例，对照组给予常规治疗，观察组在常规治疗基础上给予生长抑素辅助治疗。观察两组患者的临床疗效、总住院天数、7 d内出血复发率及不良反应。结果对照组总有效率为81.25%，观察组总有效率为93.75%，观察组总有效率高于对照组，差异有统计学意义(P<0.05)。观察组总住院天数短于对照组，差异有统计学意义(P<0.05)。对照组7 d内出血复发率为12.50%，观察组7 d内出血复发率为0，两组患者7 d内出血复发率差异有统计学意义(P<0.05)。对照者不良反应发生率为25.00%，观察组不良反应发生率为12.50%，两组患者不良反应发生率差异有统计学意义(P<0.05)。结论生长抑素辅助治疗老年急性糜烂出血性胃炎止血迅速、疗效显著且不良反应发生率低，可广泛应用于老年急性糜烂出血性胃炎的治疗。
目的：探討生長抑素輔助治療老年急性糜爛齣血性胃炎大齣血的臨床效果。方法收集2012年8月~2013年8月本院消化內科收治的急性糜爛齣血性胃炎老年患者32例，按照隨機原則將其分為觀察組和對照組各16例，對照組給予常規治療，觀察組在常規治療基礎上給予生長抑素輔助治療。觀察兩組患者的臨床療效、總住院天數、7 d內齣血複髮率及不良反應。結果對照組總有效率為81.25%，觀察組總有效率為93.75%，觀察組總有效率高于對照組，差異有統計學意義(P<0.05)。觀察組總住院天數短于對照組，差異有統計學意義(P<0.05)。對照組7 d內齣血複髮率為12.50%，觀察組7 d內齣血複髮率為0，兩組患者7 d內齣血複髮率差異有統計學意義(P<0.05)。對照者不良反應髮生率為25.00%，觀察組不良反應髮生率為12.50%，兩組患者不良反應髮生率差異有統計學意義(P<0.05)。結論生長抑素輔助治療老年急性糜爛齣血性胃炎止血迅速、療效顯著且不良反應髮生率低，可廣汎應用于老年急性糜爛齣血性胃炎的治療。
목적：탐토생장억소보조치료노년급성미란출혈성위염대출혈적림상효과。방법수집2012년8월~2013년8월본원소화내과수치적급성미란출혈성위염노년환자32례，안조수궤원칙장기분위관찰조화대조조각16례，대조조급여상규치료，관찰조재상규치료기출상급여생장억소보조치료。관찰량조환자적림상료효、총주원천수、7 d내출혈복발솔급불량반응。결과대조조총유효솔위81.25%，관찰조총유효솔위93.75%，관찰조총유효솔고우대조조，차이유통계학의의(P<0.05)。관찰조총주원천수단우대조조，차이유통계학의의(P<0.05)。대조조7 d내출혈복발솔위12.50%，관찰조7 d내출혈복발솔위0，량조환자7 d내출혈복발솔차이유통계학의의(P<0.05)。대조자불량반응발생솔위25.00%，관찰조불량반응발생솔위12.50%，량조환자불량반응발생솔차이유통계학의의(P<0.05)。결론생장억소보조치료노년급성미란출혈성위염지혈신속、료효현저차불량반응발생솔저，가엄범응용우노년급성미란출혈성위염적치료。
Objective To discuss the clinical effect of somatostatin as an adjuvant therapy on massive hemorrhage in elderly patients with acute erosive hemorrhagic gastritis. Methods Thirty-two elderly patients with acute erosive hem-orrhagic gastritis in our department of gastroenterology from August 2012 to August 2013 were selected as research ob-jects.They were evenly divided into observation group and control group in random.In the control group,patients were provided with conventional therapy,while in the observation group,adjuvant therapy of somatostatin was added on the basis of the control group.The clinical efficacy,total hospital stay,7 days hemorrhage recurrence rate and adverse reac-tions of two groups were observed. Results The total effective rate of the control group was 81.25%,of the observation group was 93.75%,the total effective rate of observation group was higher than that of control group,the difference was significant (P<0.05).The total hospital stay of observation group was shorter than that of control group,the difference was significant (P<0.05).7 days hemorrhage recurrence rate of the control group was 12.50%,of the observation group was 0,7 days hemorrhage recurrence rate of the observation group was lower than that of control group,the difference was significant (P<0.05).The incidence of adverse reactions in control group was 25.00%,in observation group was 12.50%, the incidence of adverse reactions in observation group was lower than that of control group,the difference was signifi cant (P<0.05). Conclusion Somatostatin as an adjuvant therapy can stanch bleeding quickly in elderly patients with acute erosive hemorrhagic gastritis and obtain a remarkable effect,and has a low incidence of adverse reaction,which can be widely applied to treat elderly patients with acute erosive hemorrhagic gastritis.
