CAJ | 학술논문

目的：探究发热性非溶血性输血反应(NHFTR)的临床症状表现及其防治方法。方法对本院于2010年6月~2011年12月接受输血治疗的287例患者的临床症状进行回顾性分析，观察与记录NHFTR的发生率，并行相关性分析。结果不同输血成分的NHFTR发生率比较，差异有统计学意义(P<0.05)；共有27例患者发生NHFTR，其中11例为首次受血者，16例为多次受血者，供血者的白细胞、血小板等均与NHFTR的发生有显著相关性(P<0.05)；多次受血者发生NHFTR的概率略高于首次受血者，但差异无统计学意义(P>0.05)。结论 NHFTR的发生率较高，去除血液制品中的白细胞成分，能够有效抑制血液保存过程中细胞因子含量的增加，并有效预防NHFTR。
목적：탐구발열성비용혈성수혈반응(NHFTR)적림상증상표현급기방치방법。방법대본원우2010년6월~2011년12월접수수혈치료적287례환자적림상증상진행회고성분석，관찰여기록NHFTR적발생솔，병행상관성분석。결과불동수혈성분적NHFTR발생솔비교，차이유통계학의의(P<0.05)；공유27례환자발생NHFTR，기중11례위수차수혈자，16례위다차수혈자，공혈자적백세포、혈소판등균여NHFTR적발생유현저상관성(P<0.05)；다차수혈자발생NHFTR적개솔략고우수차수혈자，단차이무통계학의의(P>0.05)。결론 NHFTR적발생솔교고，거제혈액제품중적백세포성분，능구유효억제혈액보존과정중세포인자함량적증가，병유효예방NHFTR。
Objective To explore the the clinical symptom manifestations and the prevention methods of non-hemolytic febrile transfusion reaction (NHFTR). Methods The clinical symptom of 287 patients who accepted blood transfusion treatment in our hospital from June 2012 to December 2011 were retrospectively analyzed,the incidence rate of NHFTR was observed and recorded,and correlation analysis was done. Results There was a statistical difference of morbidity rate of different blood transfusion component (P<0.05);there were 27 cases of patients with NHFTR,among them,11 pa-tients were the first blood recipients,16 patients were blood recipients more than once,the white blood cell,platelet and so on of blood donors all had significant correlation with the occurrence of NHFTR (P<0.05);the occurrence probability of NHFTR in patients with multiple blood transfusion was a little higher than that of patients with the first blood trans-fusion,but there was no statistical difference (P>0.05). Conclusion The incidence rate of NHFTR is higher,removal of white cells in blood products can effectively inhibit the increase of blood cell factor in the preservation process,and ef-fectively prevent NHFTR.