CAJ | 학술논문

目的：探讨肝病患者血清C-反应蛋白检测的临床价值。方法2011年1月~2013年12月，选取本院诊治的93例肝病患者(21例急性肝炎、39例肝硬化、33例肝癌)和90例健康体检者作为研究对象，通过免疫散射比浊法，检测各组的血清C-反应蛋白水平，比较各组的血清C-反应蛋白水平及阳性率。结果与健康者比较，肝病患者的血清C-反应蛋白水平明显升高，阳性率显著提高，差异有统计学意义(P<0.05)；急性肝炎、肝硬化、肝癌患者之间的血清C-反应蛋白水平比较，差异有统计学意义(P<0.05)，且肝病患者的血清C-反应蛋白水平与ALT、AST呈正相关。结论肝病患者的血清C-反应蛋白检测有助于评估肝内炎症活动及肝细胞受损情况，为临床诊断、治疗和预后评估提供重要依据。
목적：탐토간병환자혈청C-반응단백검측적림상개치。방법2011년1월~2013년12월，선취본원진치적93례간병환자(21례급성간염、39례간경화、33례간암)화90례건강체검자작위연구대상，통과면역산사비탁법，검측각조적혈청C-반응단백수평，비교각조적혈청C-반응단백수평급양성솔。결과여건강자비교，간병환자적혈청C-반응단백수평명현승고，양성솔현저제고，차이유통계학의의(P<0.05)；급성간염、간경화、간암환자지간적혈청C-반응단백수평비교，차이유통계학의의(P<0.05)，차간병환자적혈청C-반응단백수평여ALT、AST정정상관。결론간병환자적혈청C-반응단백검측유조우평고간내염증활동급간세포수손정황，위림상진단、치료화예후평고제공중요의거。
Objective To study the clinical value of serum C-reactive protein (CRP) for patients with liver disease. Methods 93 patients with liver disease (21 cases with acute hepatitis,39 cases with liver cirrhosis,33 cases with liver cancer) and 90 health subjects in our hospital from January 2011 to December 2013 were regarded as the research subjects.The serum CRP level in the subjects were determined by immune nephelometry methods,CRP level and its positive rate between the groups were compared. Results Compared with the health persons, the serum CRP level were significantly increased and the positive rate were obviously improved in patients with liver disease and there was a sta-tistical difference (P<0.05);and there was a statistical difference of serum CRP level between the patients with liver dis-ease including acute hepatitis,liver cirrhosis,liver cancer (P<0.05) and the serum CRP level were positive correlated with ALT and AST for patients with liver disease. Conclusion The serum CRP detection for patients with liver disease can contribute to the evaluation of liver inflammation and liver cell damage and provide the important reference for the clinical diagnosis,treatment and prognosis evaluation.