临床心身疾病杂志
臨床心身疾病雜誌
림상심신질병잡지
JOURNAL OF CLINICAL PSYCHOSOMATIC DISEASES
2014年
4期
43-46
,共4页
情感障碍%精神症状%抑郁障碍%单相抑郁%双相抑郁%汉密顿抑郁量表%阳性与阴性症状量表
情感障礙%精神癥狀%抑鬱障礙%單相抑鬱%雙相抑鬱%漢密頓抑鬱量錶%暘性與陰性癥狀量錶
정감장애%정신증상%억욱장애%단상억욱%쌍상억욱%한밀돈억욱량표%양성여음성증상량표
Affective disorder%mental symptom%depression%unipolar depression%bipolar depression%HAMD%PANSS
目的：探讨伴精神病性症状单相与双相抑郁障碍的临床特征，为临床诊断提供依据。方法将56例伴精神病性症状单相抑郁障碍患者设为单相组，53例伴精神病性症状双相抑郁障碍患者设为双相组。两组均予以艾司西酞普兰联合喹硫平治疗，双相组辅以碳酸锂治疗。采用自制一般资料调查表、汉密顿抑郁量表、阳性与阴性症状量表进行测评分析。结果双相组病程显著长于单相组（ P＜0．05或0．01），阳性精神病家族史及病前不良个性检出率显著高于单相组（ P＜0．05或0．01）；治疗前妄想、被动体验、情感低落检出率显著低于单相组（ P＜0．05或0．01），自杀观念和自杀行为检出率显著高于单相组（ P＜0．05或0．01）。结论伴精神病性症状的双相抑郁障碍与单相抑郁障碍相比，具有病程较长、家族史阳性率较高、病前不良个性较多、伴精神病性症状时间较长等特点，自杀风险较高。
目的：探討伴精神病性癥狀單相與雙相抑鬱障礙的臨床特徵，為臨床診斷提供依據。方法將56例伴精神病性癥狀單相抑鬱障礙患者設為單相組，53例伴精神病性癥狀雙相抑鬱障礙患者設為雙相組。兩組均予以艾司西酞普蘭聯閤喹硫平治療，雙相組輔以碳痠鋰治療。採用自製一般資料調查錶、漢密頓抑鬱量錶、暘性與陰性癥狀量錶進行測評分析。結果雙相組病程顯著長于單相組（ P＜0．05或0．01），暘性精神病傢族史及病前不良箇性檢齣率顯著高于單相組（ P＜0．05或0．01）；治療前妄想、被動體驗、情感低落檢齣率顯著低于單相組（ P＜0．05或0．01），自殺觀唸和自殺行為檢齣率顯著高于單相組（ P＜0．05或0．01）。結論伴精神病性癥狀的雙相抑鬱障礙與單相抑鬱障礙相比，具有病程較長、傢族史暘性率較高、病前不良箇性較多、伴精神病性癥狀時間較長等特點，自殺風險較高。
목적：탐토반정신병성증상단상여쌍상억욱장애적림상특정，위림상진단제공의거。방법장56례반정신병성증상단상억욱장애환자설위단상조，53례반정신병성증상쌍상억욱장애환자설위쌍상조。량조균여이애사서태보란연합규류평치료，쌍상조보이탄산리치료。채용자제일반자료조사표、한밀돈억욱량표、양성여음성증상량표진행측평분석。결과쌍상조병정현저장우단상조（ P＜0．05혹0．01），양성정신병가족사급병전불량개성검출솔현저고우단상조（ P＜0．05혹0．01）；치료전망상、피동체험、정감저락검출솔현저저우단상조（ P＜0．05혹0．01），자살관념화자살행위검출솔현저고우단상조（ P＜0．05혹0．01）。결론반정신병성증상적쌍상억욱장애여단상억욱장애상비，구유병정교장、가족사양성솔교고、병전불량개성교다、반정신병성증상시간교장등특점，자살풍험교고。
Objective To explore the clinical features of unipolar and bipolar disorder patients with psy-chotic symptoms (PS) in order to provide basis for clinical diagnosis .Methods Fifty-six unipolar disorder patients with PS were assigned to unipolar group and 53 bipolar ones to bipolar group .Both groups were treated with escitalopram and quetiapine ,bipolar group was plus lithium carbonate .Assessments were car-ried out with self-made general data questionnaire ,Hamilton Depression Scale (HAMD) and Positive and Negative Symptom Scale (PANSS) .Results Course was significantly longer (P<0 .05 or 0 .01) and de-tection rate of positive psychosis family history and premorbid unhealthy personality higher ( P<0 .05 or 0 .01) in bipolar than unipolar group ;detection rate of pretreatment delusion ,passive experience ,hypot-hymia was significantly lower (P<0 .05 or 0 .01) and that of suicidal ideation and behavior higher (P<0 .05 or 0 .01) in bipolar than unipolar group .Conclusion Bipolar disorder patients with PS have such characteristics as longer course ,higher positive rate of family history ,more premorbid unhealthy personal-ities ,longer psychotic symptoms and higher suicide risk compared with unipolar ones .
