CAJ | 학술논문

目的：探索和评价我国有关中成药不良反应相关文献的现状，分析原因、提出建议，旨在促进临床中成药的安全使用。方法通过检索中文期刊全文数据库（CNKI）关于中成药不良反应的文献报道，对发表时间、期刊、作者、关键词进行统计与分析。结果我国对中成药不良反应的研究呈增长趋势，已形成核心作者群，各中医药大学和医院药剂科是文献的主要来源；《中国药业》等10种期刊为报道中成药不良反应的主要期刊；临床配伍、辨证、给药途径的失误往往是造成中成药不良反应/事件的重要原因。结论我国中成药不良反应研究工作进展显著，但研究方向和方法仍需改进。
목적：탐색화평개아국유관중성약불량반응상관문헌적현상，분석원인、제출건의，지재촉진림상중성약적안전사용。방법통과검색중문기간전문수거고（CNKI）관우중성약불량반응적문헌보도，대발표시간、기간、작자、관건사진행통계여분석。결과아국대중성약불량반응적연구정증장추세，이형성핵심작자군，각중의약대학화의원약제과시문헌적주요래원；《중국약업》등10충기간위보도중성약불량반응적주요기간；림상배오、변증、급약도경적실오왕왕시조성중성약불량반응/사건적중요원인。결론아국중성약불량반응연구공작진전현저，단연구방향화방법잉수개진。
Objective To explore and evaluate the current situation of the related literature about Chinese patent drug adverse reaction in China, analyze reasons, and put forward suggestions, in order to promote the Chinese patent drug clinical medication safety. Methods To search China Journals Full-text Database (CNKI) for literatures related to adverse reaction of Chinese patent drug and then analyze the publish time, journal, author and keywords, etc. Results The research on adverse reaction of Chinese patent drug is increasing year by year and the core authors have been formed. The literatures are mostly from Chinese medicine university as well as hospitals'pharmaceutical preparation section. Ten journals, such as China Pharmaceuticals, are the core journal in this field. Errors of clinical compatibility, syn-drome differentiation and the route of administration are important causes of adverse reaction/event of Chinese medicine. Conclusion The research progress of adverse reaction of Chinese patent drug in China developed smoothly. However the research should be expanded in content and the methodology should be improved.