CAJ | 학술논문

目的：探讨乳腺导管内癌（DCIS）与浸润癌（IC）在动态增强磁共振成像（DCE-MRI）和扩散加权成像（DWI）上的影像特征，提高其影像诊断水平。方法回顾性分析10例DCIS患者（病灶13个）及10例 IC患者（病灶10个）的DCE-M RI及DWI图像，分析病灶强化形态特征、时间信号强度曲线并定量分析 ADC值。结果依据强化形态特征：DCIS强化以非块样强化中的段样强化为主，IC强化以块样强化为主，两者间差异具有统计学意义。依据时间信号强度曲线：DCIS和IC均以流出型为主，无显著性差异。依据ADC值：DCIS的平均ADC值约为（1．036±0．25）×10-3 mm2/s ， IC的平均ADC值约为（0．79±0．20）×10-3 mm2/s ，两者间差异具有统计学意义。结论结合病灶强化形态特征及ADC值，DCE-M RI联合DWI有助于乳腺导管内癌及浸润癌的鉴别诊断，提高影像诊断水平。
목적：탐토유선도관내암（DCIS）여침윤암（IC）재동태증강자공진성상（DCE-MRI）화확산가권성상（DWI）상적영상특정，제고기영상진단수평。방법회고성분석10례DCIS환자（병조13개）급10례 IC환자（병조10개）적DCE-M RI급DWI도상，분석병조강화형태특정、시간신호강도곡선병정량분석 ADC치。결과의거강화형태특정：DCIS강화이비괴양강화중적단양강화위주，IC강화이괴양강화위주，량자간차이구유통계학의의。의거시간신호강도곡선：DCIS화IC균이류출형위주，무현저성차이。의거ADC치：DCIS적평균ADC치약위（1．036±0．25）×10-3 mm2/s ， IC적평균ADC치약위（0．79±0．20）×10-3 mm2/s ，량자간차이구유통계학의의。결론결합병조강화형태특정급ADC치，DCE-M RI연합DWI유조우유선도관내암급침윤암적감별진단，제고영상진단수평。
Objective To explore image features of the breast ductal carcinoma in situ (DCIS) and invasive carcinoma (IC) in dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) and diffusion weighted imaging (DWI) for im-proving the accuracy of diagnostic imaging .Methods We retrospectively analysed 10 cases of DCIS patients (13 lesions) and 10 IC patients (10 lesions) on DCE-MRI and DWI images ,and assessed enhanced pattern features ,time signal intensi-ty curve ,and ADC value of each lesion .Results According to enhanced pattern features of the lesion ,segment enhance-ment of non blocking enhancement in DCIS and blocking enhancement in IC had statistically significant differences .Ac-cording to time signal intensity curve ,both DCIS and IC were dominated by outflow type .without no significant differ-ence .According to the ADC values of lesions ,the average ADC value of DCIS was (1 .036 ± 0 .25) × 10-3 mm2/s ,the aver-age ADC value of IC was (0 .79 ± 0 .20)× 10-3 mm2/s .The average ADC value in DCIS and IC lesions had statistically sig-nificant difference .Conclusion According to enhanced pattern features and the ADC value of lesions ,the combination of DCE-MRI and DWI is useful to differentiate ductal carcinoma in situ and invasive carcinoma for improving the accuracy of dianostic imaging .