CAJ | 학술논문

目的：探讨肝硬化并发上消化道出血的相关危险因素。方法选择2010年1月至2013年12月在我院治疗的150例肝硬化患者为研究对象，将其中并发上消化道出血的86例定为观察组，其余64例定为对照组，对两组患者的临床资料进行对比分析。结果两组的静脉曲张发生率差异有统计学意义(P<0.05)、肝功能分级差异有统计学意义(P<0.05)、门静脉高压发生率差异有统计学意义(P<0.05)、脾静脉内径、门静脉内径差异有统计学意义(P<0.05)，但两组的性别、年龄、病程等一般资料的差异无统计学意义(P>0.05)。结论食管胃府静脉曲张程度、肝功能分级、门静脉压力、门脾静脉内径均为肝硬化并发上消化道出血的相关因素，对高危患者进行积极的干预措施，对预防和治疗肝硬化的严重并发症具有重要意义。
목적：탐토간경화병발상소화도출혈적상관위험인소。방법선택2010년1월지2013년12월재아원치료적150례간경화환자위연구대상，장기중병발상소화도출혈적86례정위관찰조，기여64례정위대조조，대량조환자적림상자료진행대비분석。결과량조적정맥곡장발생솔차이유통계학의의(P<0.05)、간공능분급차이유통계학의의(P<0.05)、문정맥고압발생솔차이유통계학의의(P<0.05)、비정맥내경、문정맥내경차이유통계학의의(P<0.05)，단량조적성별、년령、병정등일반자료적차이무통계학의의(P>0.05)。결론식관위부정맥곡장정도、간공능분급、문정맥압력、문비정맥내경균위간경화병발상소화도출혈적상관인소，대고위환자진행적겁적간예조시，대예방화치료간경화적엄중병발증구유중요의의。
Objective To analyze the related risk factors of liver cirrhosis with upper gastrointestinal hemorrhage. Methods 150 patients with cirrhosis from January 2010 to December 2010 in our hospital were selected and divided into two groups according to whether they suffered from upper gastrointestinal hemorrhage (the observation group, with 86 patients in it) or not (the control group, with 64 patients in it). The primary outcome was a comparative analysis of their clinical data. Results Differences of the incidence of varicosity, rank liver function, the incidence of portal hypertension, and the differences of splenic vein diameter, portal vein diameter were statistically significant (P<0.05). The general data such as gender, age and course of disease of the the two groups were of no statistical significance (P >0.05). Conclusions Cirrhosis with upper gastrointestinal bleeding are relevant to the degree of esophagogastric varicosity, rank of liver function, portal blood pressure, and splenic vein diameter, portal vein diameter. Applying positive intervention measures for the high-risk patients is significant to prevent and treat the serious complications of liver cirrhosis.