世界科学技术-中医药现代化
世界科學技術-中醫藥現代化
세계과학기술-중의약현대화
WORLD SCIENCE AND TECHNOLOGY-MODERNIZATION OF TRADITIONAL CHINESE MEDICINE
2014年
6期
1313-1317
,共5页
赵伟%冯晓桃%李双蕾%翟琳娜%王振刚%黄蓉%陈文辉%李敏%骆峰%唐春丽%秦彦
趙偉%馮曉桃%李雙蕾%翟琳娜%王振剛%黃蓉%陳文輝%李敏%駱峰%唐春麗%秦彥
조위%풍효도%리쌍뢰%적림나%왕진강%황용%진문휘%리민%락봉%당춘려%진언
浊毒清%浊毒%解毒化浊%糖尿病性膀胱%临床观察
濁毒清%濁毒%解毒化濁%糖尿病性膀胱%臨床觀察
탁독청%탁독%해독화탁%당뇨병성방광%림상관찰
Zhuo-Du-Qing%turbid toxin%toxin-removing and turbid-descending%diabetic cystopathy%clinical observation
目的：基于浊毒理论探讨浊毒清颗粒对糖尿病性膀胱（DCP）的疗效。方法：将100例DCP 患者随机分为对照组（47例）和治疗组（53例），对照组予口服甲钴胺片治疗，治疗组则予口服浊毒清颗粒，疗程3个月。观察治疗前后膀胱残余尿量、临床表现积分、血液流变学指标、胰岛素抵抗指数 HOMA-IR 和糖化血红蛋白等指标。结果：与治疗前比较，治疗组膀胱残余尿量、临床表现积分、血液流变学指标和 HOMA-IR 均显著降低（P<0.01）；与对照组比较，治疗组治疗后膀胱残余尿、临床表现积分、血液流变学指标和 HOMA-IR 也均显著降低（P<0.01）；治疗组有效率为81.1%，明显高于对照组59.6%（P<0.05）；三大常规、肝肾功能、心电图等指标治疗前后无明显变化。结论：浊毒清颗粒对 DCP 的治疗安全有效，解毒化浊法可能是治疗 DCP 的另一有效方法，DCP 的发生发展与浊毒密切相关。
目的：基于濁毒理論探討濁毒清顆粒對糖尿病性膀胱（DCP）的療效。方法：將100例DCP 患者隨機分為對照組（47例）和治療組（53例），對照組予口服甲鈷胺片治療，治療組則予口服濁毒清顆粒，療程3箇月。觀察治療前後膀胱殘餘尿量、臨床錶現積分、血液流變學指標、胰島素牴抗指數 HOMA-IR 和糖化血紅蛋白等指標。結果：與治療前比較，治療組膀胱殘餘尿量、臨床錶現積分、血液流變學指標和 HOMA-IR 均顯著降低（P<0.01）；與對照組比較，治療組治療後膀胱殘餘尿、臨床錶現積分、血液流變學指標和 HOMA-IR 也均顯著降低（P<0.01）；治療組有效率為81.1%，明顯高于對照組59.6%（P<0.05）；三大常規、肝腎功能、心電圖等指標治療前後無明顯變化。結論：濁毒清顆粒對 DCP 的治療安全有效，解毒化濁法可能是治療 DCP 的另一有效方法，DCP 的髮生髮展與濁毒密切相關。
목적：기우탁독이론탐토탁독청과립대당뇨병성방광（DCP）적료효。방법：장100례DCP 환자수궤분위대조조（47례）화치료조（53례），대조조여구복갑고알편치료，치료조칙여구복탁독청과립，료정3개월。관찰치료전후방광잔여뇨량、림상표현적분、혈액류변학지표、이도소저항지수 HOMA-IR 화당화혈홍단백등지표。결과：여치료전비교，치료조방광잔여뇨량、림상표현적분、혈액류변학지표화 HOMA-IR 균현저강저（P<0.01）；여대조조비교，치료조치료후방광잔여뇨、림상표현적분、혈액류변학지표화 HOMA-IR 야균현저강저（P<0.01）；치료조유효솔위81.1%，명현고우대조조59.6%（P<0.05）；삼대상규、간신공능、심전도등지표치료전후무명현변화。결론：탁독청과립대 DCP 적치료안전유효，해독화탁법가능시치료 DCP 적령일유효방법，DCP 적발생발전여탁독밀절상관。
This study was aimed to explore the curative effect of Zhuo-Du-Qing (ZDQ) particles on diabetic cystopa-thy (DCP) based on the theory of turbid toxin. A total of 100 DCP patients were randomly divided into the control group with 47 cases and the treatment group with 53 cases. Mecobalamin tablets was given in the control group. And ZDQ particles were given to the treatment group. The treatment course was 3 months. The observation was made on the bladder residual urine (BRU), clinical manifestation integral, hemodynamic indexes, HOMA-IR and HbA1c before and after the treatment. The results showed that compared with pretreatment, the BRU, clinical manifestation integral, hemodynamic indexes, and HOMA-IR were significantly reduced (P < 0.01). Compared with the control group, the BRU, clinical manifestation integral, hemodynamic indexes, and HOMA-IR were also significantly reduced (P <0.01). The effective rate in the treatment group was 81.1%, which was significantly higher than 59.6% in the control group (P< 0.05). There were no obvious changes on the blood routine examination, urine routine examination, stool routine examination, liver function, renal function, electrocardiogram and so on before and after treatment. It was con-cluded that the treatment of DCP with ZDQ particles was safe and effective. To remove toxin and descend turbid may be another effective treatment method for DCP. The occurrence and development of DCP were closely related to the turbid toxin.
