CAJ | 학술논문

目的：探讨皮肤镰刀菌感染临床特点、预防及诊治经验。方法：对2001~2013年国内报道的皮肤镰刀菌感染16例进行汇集分析。结果：茄病镰刀菌感染10例，串珠镰刀菌感染3例，尖孢镰刀菌感染1例，菌种不明2例。出现皮肤溃疡12例，皮肤结节3例，同时出现皮肤溃疡及皮肤结节1例。播散性镰刀菌感染1例；基础疾病为急性白血病2例，合并皮肤鳞状细胞癌1例。真菌培养阳性16例，直接镜检发现真菌11例，病理检查发现真菌7例。全身抗真菌治疗11例，好转或痊愈8例。结论：皮肤镰刀菌感染以茄病镰刀菌最多见，皮肤呈溃疡或结节样改变多见。真菌培养、直接镜检及组织病理学检查有助诊断，治疗尚无统一方案。
목적：탐토피부렴도균감염림상특점、예방급진치경험。방법：대2001~2013년국내보도적피부렴도균감염16례진행회집분석。결과：가병렴도균감염10례，천주렴도균감염3례，첨포렴도균감염1례，균충불명2례。출현피부궤양12례，피부결절3례，동시출현피부궤양급피부결절1례。파산성렴도균감염1례；기출질병위급성백혈병2례，합병피부린상세포암1례。진균배양양성16례，직접경검발현진균11례，병리검사발현진균7례。전신항진균치료11례，호전혹전유8례。결론：피부렴도균감염이가병렴도균최다견，피부정궤양혹결절양개변다견。진균배양、직접경검급조직병이학검사유조진단，치료상무통일방안。
Objective:To investigate the clinical features and treatment of skin Fusarium infection. Methods:Sixteen cases of skin fusariun infections reported in China from 2001 to 2003 were collected and analyzed. Results:There were 10 cases of Fusarium solani infection,3 cases of Fusarium moniliforme infection,1 case of Fusarium oxysporum infection and 2 cases of unknown species in this group. Skin ulcer occurred in 12 cases,skin nodules in 3 cases,and skin ulcer and nodules in 1 case. One case presented disseminated Fusarium infection,2 cases the basic disease of acute leukemia and 1 case was complicated with squamouscell carcinoma. Fungal culture was proved positive in 16 cases;fungal component was detected by direct microscopy in 11 cases and by pathological examination in 7 cases. 11 cases were treated with systemicantifungal therapy, and 8 of them were improved or cured. Conclusions:Fusarium solani is most commonly seen in Fusarium infection, presenting the symptoms of skin lesion, ulcer or nodular changes in general. Fungal culture,direct microscopic examination and histopathology examination are helpful to the diagnosis. There is no unified treatment protocol for Fusarium infection up to now.