中国麻风皮肤病杂志
中國痳風皮膚病雜誌
중국마풍피부병잡지
CHINA JOURNAL OF LEPROSY AND SKIN DISEASES
2014年
7期
400-401
,共2页
刘志芳%马元龙%阿拉腾楚鲁%于希军%贺伟
劉誌芳%馬元龍%阿拉騰楚魯%于希軍%賀偉
류지방%마원룡%아랍등초로%우희군%하위
梅毒%梅毒螺旋体%髓样分化因子 88%核因子-κB%肿瘤坏死因子-α
梅毒%梅毒螺鏇體%髓樣分化因子 88%覈因子-κB%腫瘤壞死因子-α
매독%매독라선체%수양분화인자 88%핵인자-κB%종류배사인자-α
syphilis%treponema pallidum%MyD88%NF-κB%TNF-α
目的：检测髓样分化因子88(MyD88)、核因子-κB(NF-κB)及肿瘤坏死因子-α(TNF-α)在梅毒患者血清中的表达。方法：采用 ELISA 方法检测82例临床确诊的一期及二期梅毒患者与48名正常人血清 MyD88、NF-κB 和 TNF-α水平。结果：82例梅毒患者血清中 MyD88、NF-κB 及 TNF-α水平均高于正常对照组，两者比较差异均有显著性(P<0.001)。结论： MyD88、NF-κB 和 TNF-α可能与 TP 感染机体后的免疫应答有关。
目的：檢測髓樣分化因子88(MyD88)、覈因子-κB(NF-κB)及腫瘤壞死因子-α(TNF-α)在梅毒患者血清中的錶達。方法：採用 ELISA 方法檢測82例臨床確診的一期及二期梅毒患者與48名正常人血清 MyD88、NF-κB 和 TNF-α水平。結果：82例梅毒患者血清中 MyD88、NF-κB 及 TNF-α水平均高于正常對照組，兩者比較差異均有顯著性(P<0.001)。結論： MyD88、NF-κB 和 TNF-α可能與 TP 感染機體後的免疫應答有關。
목적：검측수양분화인자88(MyD88)、핵인자-κB(NF-κB)급종류배사인자-α(TNF-α)재매독환자혈청중적표체。방법：채용 ELISA 방법검측82례림상학진적일기급이기매독환자여48명정상인혈청 MyD88、NF-κB 화 TNF-α수평。결과：82례매독환자혈청중 MyD88、NF-κB 급 TNF-α수평균고우정상대조조，량자비교차이균유현저성(P<0.001)。결론： MyD88、NF-κB 화 TNF-α가능여 TP 감염궤체후적면역응답유관。
To measure the expression of MyD-88, NF-κB and TNF-α in the sera of patients with syphilis. Methods: Eighty-two patients with syphilis and forty eight healthy controls were recruited into the study. The expression of MyD-88, NF-κB and TNF-α were measured with ELISA. Results: The levels of MyD88, NF-κB and TNF-α in patients with syphilis were significantly higher than those in healthy controls (P<0.001). Conclusion: MyD88 and NF-κB may play a part of role in the immune response to treponema pallidum infection.
