CAJ | 학술논문

目的：探讨磁共振弹性成像（magnetic resonance elastography ，MRE）对主动脉壁弹性评价的可行性。方法制作血管模型的体模，采用离体猪主动脉、不同弹性的厚壁乳胶管和薄壁软胶管，三种血管模型包埋在弹性B-凝胶深部。三种血管模型内注入生理盐水。采用气动的驱动装置放置在体模表面，产生低频率机械波向体模内传播。采用M RE序列进行扫描，对体模内产生的机械波进行成像。结果机械波可以传播到体模深部血管模型的管腔中，三种不同血管模型内显示了机械波的良好传播。机械波沿着血管模型的长轴进行传播。在三种不同弹性的血管模型中机械波的波长变化明显，而且两种不同频率之间波长也相应变化。均与其物理特性相符，验证了成像的有效性。结论初步的探索显示M RE技术对主动脉壁弹性成像具有潜在可行性，值得进一步深入研究。
목적：탐토자공진탄성성상（magnetic resonance elastography ，MRE）대주동맥벽탄성평개적가행성。방법제작혈관모형적체모，채용리체저주동맥、불동탄성적후벽유효관화박벽연효관，삼충혈관모형포매재탄성B-응효심부。삼충혈관모형내주입생리염수。채용기동적구동장치방치재체모표면，산생저빈솔궤계파향체모내전파。채용M RE서렬진행소묘，대체모내산생적궤계파진행성상。결과궤계파가이전파도체모심부혈관모형적관강중，삼충불동혈관모형내현시료궤계파적량호전파。궤계파연착혈관모형적장축진행전파。재삼충불동탄성적혈관모형중궤계파적파장변화명현，이차량충불동빈솔지간파장야상응변화。균여기물리특성상부，험증료성상적유효성。결론초보적탐색현시M RE기술대주동맥벽탄성성상구유잠재가행성，치득진일보심입연구。
Objective To investigate the feasibility of magnetic resonance elastography (MRE) technique in the evalua-tion of the elasticity of aortic wall .Methods A phantom study was performed .An ex vivo porcine aorta ,a thick-walled as well as a thin-walled latex tube were parallelly embedded in the bottom of the B-gel phantom .The vessel models were filled with normal saline and were imaged with a gradient-echo MRE imaging sequence ,and a small pneumatic passive driv-er applied to the surface of the phantom to generate mechanical waves within the vessel models .Results The mechanical waves were well transmitted to the vessel models embedded in the bottom of B-gel .The mechanical waves were well visu-alized within the vessel models propagating longitudinally along the vessel lumen .The wavelength change was well defined among the three vessel models with different elasticity .The wavelength change was also identified between different fre-quencies .These findings were consistent with physical characteristics and verified the effectiveness of the hypothesis .Con-clusion The study shows that MRE technique is feasible and potentially useful for assessing the elastic properties of aor-ta ,and merits further investigation .