实用心脑肺血管病杂志
實用心腦肺血管病雜誌
실용심뇌폐혈관병잡지
PRACTICAL JOURNAL OF CARDIAC CEREBRAL PNEUMAL AND VASCULAR DISEASE
2014年
7期
64-65
,共2页
心肌梗死%利钠肽,脑%心功能
心肌梗死%利鈉肽,腦%心功能
심기경사%리납태,뇌%심공능
Myocardial infarction%Natriuretic peptide,brain%Cardiac function
目的：研究急性心肌梗死（AMI）患者血浆脑钠肽（BNP）水平与梗死部位和心功能的关系。方法选择2012年6月-2013年6月在我科住院的 ST 段抬高 AMI 患者50例为 AMI 组，同期在我院体检健康者50例为对照组。检测两组受试者的血浆 BNP 水平，分析其与梗死部位、左室射血分数（LVEF）及 Killip 分级的关系。结果 AMI组患者血浆 BNP 水平为（6357.07±3772.57）ng/ L，明显高于对照组的（65.75±64.36）ng/ L（P <0.05）。不同梗死部位 AMI 患者血浆 BNP 水平比较，差异无统计学意义（P >0.05）。单因素 COX 回归分析结果显示，血浆 BNP 水平与 LVEF 呈负相关（OR ＝-0.47，P <0.05）。不同 Killip 分级 AMI 患者血浆 BNP 水平比较，差异有统计学意义（P <0.05）。结论 AMI 患者血浆 BNP 水平明显升高，其与梗死部位无关，与 LVEF 及 Killip 分级相关，可作为评价 AMI 患者心功能的参考指标。
目的：研究急性心肌梗死（AMI）患者血漿腦鈉肽（BNP）水平與梗死部位和心功能的關繫。方法選擇2012年6月-2013年6月在我科住院的 ST 段抬高 AMI 患者50例為 AMI 組，同期在我院體檢健康者50例為對照組。檢測兩組受試者的血漿 BNP 水平，分析其與梗死部位、左室射血分數（LVEF）及 Killip 分級的關繫。結果 AMI組患者血漿 BNP 水平為（6357.07±3772.57）ng/ L，明顯高于對照組的（65.75±64.36）ng/ L（P <0.05）。不同梗死部位 AMI 患者血漿 BNP 水平比較，差異無統計學意義（P >0.05）。單因素 COX 迴歸分析結果顯示，血漿 BNP 水平與 LVEF 呈負相關（OR ＝-0.47，P <0.05）。不同 Killip 分級 AMI 患者血漿 BNP 水平比較，差異有統計學意義（P <0.05）。結論 AMI 患者血漿 BNP 水平明顯升高，其與梗死部位無關，與 LVEF 及 Killip 分級相關，可作為評價 AMI 患者心功能的參攷指標。
목적：연구급성심기경사（AMI）환자혈장뇌납태（BNP）수평여경사부위화심공능적관계。방법선택2012년6월-2013년6월재아과주원적 ST 단태고 AMI 환자50례위 AMI 조，동기재아원체검건강자50례위대조조。검측량조수시자적혈장 BNP 수평，분석기여경사부위、좌실사혈분수（LVEF）급 Killip 분급적관계。결과 AMI조환자혈장 BNP 수평위（6357.07±3772.57）ng/ L，명현고우대조조적（65.75±64.36）ng/ L（P <0.05）。불동경사부위 AMI 환자혈장 BNP 수평비교，차이무통계학의의（P >0.05）。단인소 COX 회귀분석결과현시，혈장 BNP 수평여 LVEF 정부상관（OR ＝-0.47，P <0.05）。불동 Killip 분급 AMI 환자혈장 BNP 수평비교，차이유통계학의의（P <0.05）。결론 AMI 환자혈장 BNP 수평명현승고，기여경사부위무관，여 LVEF 급 Killip 분급상관，가작위평개 AMI 환자심공능적삼고지표。
Objective To study the relationship of plasma brain natriuretic peptide(BNP) level to infarction posi-tions and heart function in patients with acute myocardial infarction(AMI). Methods From June 2012 to June 2013,50 AMI patients with ST - segment elevation in our hospital were selected as AMI group,and 50 healthy people selected as control group. Plasma BNP level was detected in AMI group and control group,and its correlation with infarction positions,left ventricu-lar ejection fraction( LVEF) and Killip systematics was analyzed. Results The plasma BNP level in AMI group was(6 357. 07 ± 3 772. 57)ng/ L,was significantly higher than that in control group of(65. 75 ± 64. 36)ng/ L(P < 0. 05). There was no significant differences of plasma BNP levels in AMI patients with different infarction positions(P > 0. 05),but there was in AMI patients with different Killip systematics(P < 0. 05). By univariate COX regression analysis,plasma BNP level was neg-atively correlated with LVEF(OR = - 0. 47,P < 0. 05). Conclusion Plasma BNP level is significantly elevated in AMI pa-tients,and is not correlated with infarction positions,but with LVEF and Killip systematics,and it can be used as an important predictor for left ventricular function in AMI patients.
