世界中医药
世界中醫藥
세계중의약
WORLD CHINESE MEDICINE
2014年
7期
931-933
,共3页
范桂清%张万龙%汪芗%钟亚彬%李永红%王惠敏%张俞%王丹
範桂清%張萬龍%汪薌%鐘亞彬%李永紅%王惠敏%張俞%王丹
범계청%장만룡%왕향%종아빈%리영홍%왕혜민%장유%왕단
针刺%第三腰椎横突综合征%白细胞介素6%白细胞介素10%镇痛机制
針刺%第三腰椎橫突綜閤徵%白細胞介素6%白細胞介素10%鎮痛機製
침자%제삼요추횡돌종합정%백세포개소6%백세포개소10%진통궤제
Acupuncture%ThirdLumbarTrans-verseProcessSyndrome%Interleukin-6%Interleukin-10%AnalgesicMechanism
目的:观察针刺治疗第三腰椎横突综合征的止痛作用,并探讨其镇痛机制。方法:对40例第三腰椎横突综合征患者进行针刺治疗(穴取横突处阿是穴、肾俞、委中,3次/周,3周为1个研究周期);并于治疗前(第0周)、治疗后(第3周)、回访时(第5周)用视觉模拟评分法(Visual Analogue Scale,VAS)进行疼痛评分;并用酶联免疫吸附试验(Enzyme Linked Immunosorbent As-say,ELISA)法检测血清白细胞介素6(Interleukin-6,IL-6)、白细胞介素10(Interleukin-10,IL-10)的水平。结果:治疗后(第3周)时,VAS值下降(P<0.05),血清IL-6、IL-10水平上升(P<0.05);回访时(第5周)VAS值下降(P<0.05),血清IL-6、IL-10水平下降(P<0.05)。结论:针刺对第三腰椎横突综合征有很好的止痛作用,其镇痛机制很可能是促进细胞因子的代谢进程。
目的:觀察針刺治療第三腰椎橫突綜閤徵的止痛作用,併探討其鎮痛機製。方法:對40例第三腰椎橫突綜閤徵患者進行針刺治療(穴取橫突處阿是穴、腎俞、委中,3次/週,3週為1箇研究週期);併于治療前(第0週)、治療後(第3週)、迴訪時(第5週)用視覺模擬評分法(Visual Analogue Scale,VAS)進行疼痛評分;併用酶聯免疫吸附試驗(Enzyme Linked Immunosorbent As-say,ELISA)法檢測血清白細胞介素6(Interleukin-6,IL-6)、白細胞介素10(Interleukin-10,IL-10)的水平。結果:治療後(第3週)時,VAS值下降(P<0.05),血清IL-6、IL-10水平上升(P<0.05);迴訪時(第5週)VAS值下降(P<0.05),血清IL-6、IL-10水平下降(P<0.05)。結論:針刺對第三腰椎橫突綜閤徵有很好的止痛作用,其鎮痛機製很可能是促進細胞因子的代謝進程。
목적:관찰침자치료제삼요추횡돌종합정적지통작용,병탐토기진통궤제。방법:대40례제삼요추횡돌종합정환자진행침자치료(혈취횡돌처아시혈、신유、위중,3차/주,3주위1개연구주기);병우치료전(제0주)、치료후(제3주)、회방시(제5주)용시각모의평분법(Visual Analogue Scale,VAS)진행동통평분;병용매련면역흡부시험(Enzyme Linked Immunosorbent As-say,ELISA)법검측혈청백세포개소6(Interleukin-6,IL-6)、백세포개소10(Interleukin-10,IL-10)적수평。결과:치료후(제3주)시,VAS치하강(P<0.05),혈청IL-6、IL-10수평상승(P<0.05);회방시(제5주)VAS치하강(P<0.05),혈청IL-6、IL-10수평하강(P<0.05)。결론:침자대제삼요추횡돌종합정유흔호적지통작용,기진통궤제흔가능시촉진세포인자적대사진정。
To observe the analgesic efficacy of acupuncture treatment on the third lumbar trans-verse process syndrome,and to explore the analgesic mechanism.Methods:Forty patients with the third lumbar trans-verse process syndrome were given acupuncture therapy in acupoints of ashi(on transverse),Shenshu(BL-23),Weizhong(BL-40)with 3sessions a week,3 weeks as a course.The pain (VAS)and the level of interleukin-6,interleukin-1 0 in the serum detected by ELISA after treatment (on the third week)and re-turned visit (on the fifth week)were recorded.Results:After 3 weeks of treatment,the score of VAS decreased (P<0.05 ),and the level of interleukin-6 and interleukin-1 0 in the serum were increased (P<0.05 ).In the return visit,the value of VAS decreased (P<0.05),and the level of interleukin-6,interleukin-1 0 in the serum were fallen (P<0.05).Conclusion:Acupuncture treatment on the third lumbar trans-verse process syndrome had a better analgesic effect,and its analgesic mechanism may be promoting the metabolism of cytokines.