世界中医药
世界中醫藥
세계중의약
WORLD CHINESE MEDICINE
2014年
7期
880-882
,共3页
过敏性鼻炎%西替利嗪%玉屏风散
過敏性鼻炎%西替利嗪%玉屏風散
과민성비염%서체리진%옥병풍산
Allergicrhinitis%Cetirizine%YuPingFengSan
目的：探讨过敏性鼻炎（AR）的治疗方法及西替利嗪联合玉屏风散对AR的疗效。方法：采用随机数字表法，将120例AR患者分为2组，每组60例，对照组口服西替利嗪1次/d，10 mg/次；观察组在对照组基础上，水煎服玉屏风散1剂/d，早晚各服1次，共400 mL。连续用药14 d为1个疗程，2个疗程后比较2组临床疗效、临床症状消失时间、症状评分及不良反应情况等。结果：观察组治疗1个疗程和2个疗程后总有效率分别达到83.33％和95.00％，显著高于对照组；鼻塞、鼻痒、喷嚏和流涕症状消失的时间分别为（6.12±2.43）d、（7.65±2.59）d、（3.27±1.86）d和（3.11±1.42）d，均显著早于对照组各症状的消失时间（P＜0.05）；症状体征总积分为（2.57±1.04）分，显著低于对照组（3.86±1.20）分（P＜0.05）；总不良反应率和复发率仅为6.67％和11.67％，显著低于对照组（P＜0.05）。结论：西替利嗪联合玉屏风散治疗过敏性鼻炎，起效快，效果好，不良反应少，临床疗效确切。
目的：探討過敏性鼻炎（AR）的治療方法及西替利嗪聯閤玉屏風散對AR的療效。方法：採用隨機數字錶法，將120例AR患者分為2組，每組60例，對照組口服西替利嗪1次/d，10 mg/次；觀察組在對照組基礎上，水煎服玉屏風散1劑/d，早晚各服1次，共400 mL。連續用藥14 d為1箇療程，2箇療程後比較2組臨床療效、臨床癥狀消失時間、癥狀評分及不良反應情況等。結果：觀察組治療1箇療程和2箇療程後總有效率分彆達到83.33％和95.00％，顯著高于對照組；鼻塞、鼻癢、噴嚏和流涕癥狀消失的時間分彆為（6.12±2.43）d、（7.65±2.59）d、（3.27±1.86）d和（3.11±1.42）d，均顯著早于對照組各癥狀的消失時間（P＜0.05）；癥狀體徵總積分為（2.57±1.04）分，顯著低于對照組（3.86±1.20）分（P＜0.05）；總不良反應率和複髮率僅為6.67％和11.67％，顯著低于對照組（P＜0.05）。結論：西替利嗪聯閤玉屏風散治療過敏性鼻炎，起效快，效果好，不良反應少，臨床療效確切。
목적：탐토과민성비염（AR）적치료방법급서체리진연합옥병풍산대AR적료효。방법：채용수궤수자표법，장120례AR환자분위2조，매조60례，대조조구복서체리진1차/d，10 mg/차；관찰조재대조조기출상，수전복옥병풍산1제/d，조만각복1차，공400 mL。련속용약14 d위1개료정，2개료정후비교2조림상료효、림상증상소실시간、증상평분급불량반응정황등。결과：관찰조치료1개료정화2개료정후총유효솔분별체도83.33％화95.00％，현저고우대조조；비새、비양、분체화류체증상소실적시간분별위（6.12±2.43）d、（7.65±2.59）d、（3.27±1.86）d화（3.11±1.42）d，균현저조우대조조각증상적소실시간（P＜0.05）；증상체정총적분위（2.57±1.04）분，현저저우대조조（3.86±1.20）분（P＜0.05）；총불량반응솔화복발솔부위6.67％화11.67％，현저저우대조조（P＜0.05）。결론：서체리진연합옥병풍산치료과민성비염，기효쾌，효과호，불량반응소，림상료효학절。
To investigate the curative effective of Cetirizine combined with Yupingfeng San in treating allergicrhinitis (AR). Methods:One hundred and twenty patients with AR were divided into two groups according to the random number table and there were 60 cases in each group.The control group applied daily oral administration ofhttp://dict.baidu.com/s?wd =%20profess%20to%20be%20convinced-#cetirizine 1 0 mg/time.Patients in the observation group were given 400 ml of Yu Ping Feng San in the mornings and evenings except from the same treatment as the control group.The clinical efficacy,disappearance time of clinical symptoms,symp-tom score and adverse effects of the two groups were compared after 2 courses of treatment.Results:The total effective rate of the obser-vation group after one treatment course and two treatment courses were 83.33% and 95% respectively,which were both significantly higher than those of the control group.The disappearance time of nasal congestion,nasal itching,sneezing and runny nose symptoms in the observation group were (6.1 2 ±2.43)d,(7.65 ±2.59)d,(3.27 ±1 .86)d and (3.1 1 ±1 .42)d respectively,which were all significantly shorter than those of the control group (P<0.05).The overall symptom score in the observation group was (2.57 ±1 . 04)points,significantly lower than that of the control group (3.86 ±1 .20)points (P<0.05).The total adverse reaction rate and re-currence rate was only 6.67% and 1 1 .67% in the observation group,significantly lower than that of the control group (P<0.05 ). Conclusion:Cetirizine combined with Yuping Feng San could significantly improve the symptom of allergicrhinitis and reduce the ad-verse reactions and the clinical curative effect is definite.
