CAJ | 학술논문

目的：探讨降钙素原在扩张性心肌病合并感染患者中的诊断价值。方法回顾性分析我院近年来收治的71例扩张性心肌病患者的临床资料,将合并感染的患者定为感染组,其余患者作为对照组,检测入院治疗前后患者血清降钙素原的水平。结果62例患者治疗好转出院,9例患者死亡,死亡率14.52%；感染组患者在入院后降钙素原水平(11.37±3.17)ng/ mL 显著高于对照组(0.29±0.18)ng/ mL；抗生素治疗后恢复期感染组降钙素原水平大幅度下降(0.30±0.26)ng/ mL,与对照组(0.28±0.19)ng/ mL 相比差异无统计学意义；血清降钙素原诊断扩张性心肌病合并感染的灵敏度为89.47%,特异度为90.90%。结论血清降钙素原可以作为扩张性心肌病合并感染较为理想的诊断及治疗效果评估标志物。
목적：탐토강개소원재확장성심기병합병감염환자중적진단개치。방법회고성분석아원근년래수치적71례확장성심기병환자적림상자료,장합병감염적환자정위감염조,기여환자작위대조조,검측입원치료전후환자혈청강개소원적수평。결과62례환자치료호전출원,9례환자사망,사망솔14.52%；감염조환자재입원후강개소원수평(11.37±3.17)ng/ mL 현저고우대조조(0.29±0.18)ng/ mL；항생소치료후회복기감염조강개소원수평대폭도하강(0.30±0.26)ng/ mL,여대조조(0.28±0.19)ng/ mL 상비차이무통계학의의；혈청강개소원진단확장성심기병합병감염적령민도위89.47%,특이도위90.90%。결론혈청강개소원가이작위확장성심기병합병감염교위이상적진단급치료효과평고표지물。
Objective To investigate the diagnostic value of procalcitonin in patients with dilated cardiomyopathy compli-cated infection. Methods The clinical data of 71 patients with dilated cardiomyopathy were retrospectively studied in our hospi-tal. The 71 patients were classified into infection group and the rest of the patients as control group. The serum level of procalcito-nin was detected. Results Of the patients, 9 cases died and the mortality rate was 14. 52% . The procalcitonin level in infected group was significantly higher than the control group before treatment (11. 37 ± 3. 17)ng/ mL versus (0. 29 ± 0. 18)ng/ mL. After treatment the procalcitonin level in the infection group dramatically dropped, with no significant difference to the control group (0. 30 ± 0. 26)ng/ mL versus(0. 28 ± 0. 19)ng/ mL. The sensitivity and specificity of serum procalcitonin in diagnosing dilated car-diomyopathy combined infection was 89. 47% and 90. 90% , respectively. Conclusion Serum procalcitonin can be used as an i-deal marker in the diagnosis and treatment of dilated cardiomyopathy combined with infection.