中国实用神经疾病杂志
中國實用神經疾病雜誌
중국실용신경질병잡지
CHINESE JOURNAL OF PRACTICAL NERVOUS DISEASES
2014年
13期
24-26
,共3页
依达拉奉%尼莫通%急性脑梗死%神经功能缺损评分
依達拉奉%尼莫通%急性腦梗死%神經功能缺損評分
의체랍봉%니막통%급성뇌경사%신경공능결손평분
Edaravone%Nimodipine%Acute cerebral infarction%Nerve function deficit score
目的：研究依达拉奉（Edaravone ，EDA）联合尼莫通（Nimoldipine ，NMP）对急性脑梗死（acute cerebral infarc-tion ，ACI）患者的疗效及对神经功能缺损评分（Neural function defect score ，NFDS）的影响。方法选取我院2010-07-2013-07就诊的180例ACI病患，随机分成3组，每组60例。EDA组只给予 EDA 治疗，NM P组只给予 NM P治疗，联合组给予EDA联合NMP治疗。比较3组治疗前后NFDS变化及疗效。结果3组在治疗后NFDS评分都显著下降，其中联合组治疗后NFDS评分为（8.18±2.12）分下降程度最大，其次是EDA组（11.86±2.27）分，最次为NMP组（14.22±2.52）分。联合组愈显率为73.33％（44／60），总有效率是91.67％（55／60），较 EDA 组的48.33％（29／60），76.67％（46／60），以及 NMP组的43.33％（26／60），73.33％（44／60）明显升高，差异均具有统计学意义（均 P＜0.05）。结论 EDA联合NMP治疗ACI ，能有效改善病患N FDS评分，疗效显著，值得推荐。
目的：研究依達拉奉（Edaravone ，EDA）聯閤尼莫通（Nimoldipine ，NMP）對急性腦梗死（acute cerebral infarc-tion ，ACI）患者的療效及對神經功能缺損評分（Neural function defect score ，NFDS）的影響。方法選取我院2010-07-2013-07就診的180例ACI病患，隨機分成3組，每組60例。EDA組隻給予 EDA 治療，NM P組隻給予 NM P治療，聯閤組給予EDA聯閤NMP治療。比較3組治療前後NFDS變化及療效。結果3組在治療後NFDS評分都顯著下降，其中聯閤組治療後NFDS評分為（8.18±2.12）分下降程度最大，其次是EDA組（11.86±2.27）分，最次為NMP組（14.22±2.52）分。聯閤組愈顯率為73.33％（44／60），總有效率是91.67％（55／60），較 EDA 組的48.33％（29／60），76.67％（46／60），以及 NMP組的43.33％（26／60），73.33％（44／60）明顯升高，差異均具有統計學意義（均 P＜0.05）。結論 EDA聯閤NMP治療ACI ，能有效改善病患N FDS評分，療效顯著，值得推薦。
목적：연구의체랍봉（Edaravone ，EDA）연합니막통（Nimoldipine ，NMP）대급성뇌경사（acute cerebral infarc-tion ，ACI）환자적료효급대신경공능결손평분（Neural function defect score ，NFDS）적영향。방법선취아원2010-07-2013-07취진적180례ACI병환，수궤분성3조，매조60례。EDA조지급여 EDA 치료，NM P조지급여 NM P치료，연합조급여EDA연합NMP치료。비교3조치료전후NFDS변화급료효。결과3조재치료후NFDS평분도현저하강，기중연합조치료후NFDS평분위（8.18±2.12）분하강정도최대，기차시EDA조（11.86±2.27）분，최차위NMP조（14.22±2.52）분。연합조유현솔위73.33％（44／60），총유효솔시91.67％（55／60），교 EDA 조적48.33％（29／60），76.67％（46／60），이급 NMP조적43.33％（26／60），73.33％（44／60）명현승고，차이균구유통계학의의（균 P＜0.05）。결론 EDA연합NMP치료ACI ，능유효개선병환N FDS평분，료효현저，치득추천。
Objective tostudytheeffectivenessofedaravone(EDA)combinedwithnimodipine(NMP)onpatientswitha-cute cerebral infarction(ACI) and their effects on the nerve function deficit score (NFDS).Methods 108 cases of patients with ACI in our hospital from July 2010 to July 2013 were randomly divided into three groups. EDA group was treated with EDA , NMP group was treated with NMP ,combined group was treated with EDA and NMP. The clinical effectiveness and NFDS changes of three groups were compared.Results The NFDS of three groups after treatment were significantly decreased. The NFDS score of the combined group after treatment [(8.18 ± 2.12)piont] was the most obviously declined ,followed by EDA Group [(11.86 ± 2.27)piont] ,and then NMP Group [(14.22 ± 2.52)piont].The combined group’s markedly effective rate [73.33% (44/60)] ,the total efficiency [91.67% (55/60)] were significantly higher than EDA group’s [48.33% (29/60) , 76.67% (46/60)];NMP group’s [43.33% (26/60) ,73.33% (44/60)].The differences were statistically significant (P<0.05).Conclusion EDA combined with NMP can effectively improve NFDS score of patients with ACI and is worthy of recom-mendation.
