中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2014年
11期
1670-1672
,共3页
心房颤动%C反应蛋白质%N-末端脑钠肽前体%参松养心胶囊
心房顫動%C反應蛋白質%N-末耑腦鈉肽前體%參鬆養心膠囊
심방전동%C반응단백질%N-말단뇌납태전체%삼송양심효낭
Atrial fibrillation%C-reactive protein%N-terminal pro-brain natriuretic peptide%Shensongyangxin capsule
目的 探讨参松养心胶囊对持续性心房颤动(简称房颤)患者复律后血浆超敏C反应蛋白(hs-CRP)和N-末端脑钠肽前体(NT-proBNP)的影响.方法 152例持续性房颤患者按照数字表法随机分为两组各76例,两组均进行房颤复律.随访12个月.测定治疗前后血浆hs-CRP和NT-proBNP.结果 所有房颤患者经复律后转复为窦性心律,在12个月的随访中,观察组有2例患者房颤复发,对照组9例复发,两组差异有统计学意义(x2=5.28,P＜0.05).两组hs-CRP和NT-proBNP在治疗后均明显降低(t=7.270、3.601、8.118、3.006,P＜0.05,P＜0.01),并且观察组降低程度更加明显(t=4.720、2.914,均P＜0.05).结论 参松养心胶囊可以明显减轻持续性房颤患者复律后血浆hs-CRP和NT-proBNP的表达.
目的 探討參鬆養心膠囊對持續性心房顫動(簡稱房顫)患者複律後血漿超敏C反應蛋白(hs-CRP)和N-末耑腦鈉肽前體(NT-proBNP)的影響.方法 152例持續性房顫患者按照數字錶法隨機分為兩組各76例,兩組均進行房顫複律.隨訪12箇月.測定治療前後血漿hs-CRP和NT-proBNP.結果 所有房顫患者經複律後轉複為竇性心律,在12箇月的隨訪中,觀察組有2例患者房顫複髮,對照組9例複髮,兩組差異有統計學意義(x2=5.28,P＜0.05).兩組hs-CRP和NT-proBNP在治療後均明顯降低(t=7.270、3.601、8.118、3.006,P＜0.05,P＜0.01),併且觀察組降低程度更加明顯(t=4.720、2.914,均P＜0.05).結論 參鬆養心膠囊可以明顯減輕持續性房顫患者複律後血漿hs-CRP和NT-proBNP的錶達.
목적 탐토삼송양심효낭대지속성심방전동(간칭방전)환자복률후혈장초민C반응단백(hs-CRP)화N-말단뇌납태전체(NT-proBNP)적영향.방법 152례지속성방전환자안조수자표법수궤분위량조각76례,량조균진행방전복률.수방12개월.측정치료전후혈장hs-CRP화NT-proBNP.결과 소유방전환자경복률후전복위두성심률,재12개월적수방중,관찰조유2례환자방전복발,대조조9례복발,량조차이유통계학의의(x2=5.28,P＜0.05).량조hs-CRP화NT-proBNP재치료후균명현강저(t=7.270、3.601、8.118、3.006,P＜0.05,P＜0.01),병차관찰조강저정도경가명현(t=4.720、2.914,균P＜0.05).결론 삼송양심효낭가이명현감경지속성방전환자복률후혈장hs-CRP화NT-proBNP적표체.
Objective To explore the influence of Shensongyangxin capsule on plasma high-sensitivity C-reactive protein(hs-CRP) and N-terminal pro-brain natriuretic peptide(NT-proBNP) in patients with persistent atrial fibrillation after cardioversion.Methods 152 patients with persistent atrial fibrillation were randomly divided into the observation group(76 cases)and the control group (76 cases).All patients were conducted atrial cardioversion.The patients were followed up for 12 months.The plasma hs-CRP and NT-proBNP were measured before and after treatment.Results All patients with atrial fibrillation were cardioversed to sinus rhythm after cardioversion.During 12 months of follow-up,in the observation group 2 patients had recurrence of atrial fibrillation and in the control group,nine cases of recurrence,the difference between the two groups was significant (x2 =5.28,P ＜ 0.05).After treatment,the plasma hs-CRP and NT-proBNP in the two groups were significantly decreased(t =7.270,3.601,8.118,3.006,P ＜ 0.05,P ＜ 0.01),and those in the observation group were significantly lower than control group (t =4.720,2.914,all P ＜ 0.05).Conclusion Shensongyangxin capsule can significantly reduce plasma hs-CRP and NT-proBNP in patients with persistent atrial fibrillation after cardioversion.
