CAJ | 학술논문

目的：观察脑心通胶囊联合氟桂利嗪胶囊治疗慢性脑供血不足的临床疗效。方法将96例慢性脑供血不足患者按就诊顺序号随机分为治疗组和对照组,每组46例。治疗组予脑心通胶囊联合氟桂利嗪胶囊综合治疗,对照组予氟桂利嗪胶囊等西药常规治疗,连用2个月。观察2组临床疗效,并采用经颅多普勒(TCD)检测2组大脑中动脉(MCA)、椎动脉(VA)、基底动脉(BA)的平均血流速度(Vm)。结果治疗组总有效率为95.65%(44/46),对照组为73.91%(34/46),2组比较差异有统计学意义(P＜0.05)。治疗1个月,2组MCA、VA、BA的Vm均较治疗前略有增加,但差异无统计学意义(P＞0.05)；治疗2个月,治疗组患者MCA、VA、BA的Vm均较治疗前明显增加(P＜0.05),与对照组比较差异有统计学意义(P＜0.05)。结论脑心通胶囊联合氟桂利嗪胶囊治疗慢性脑供血不足,在缓解症状、改善血流动力学方面均较单纯西药治疗有明显优势。
목적：관찰뇌심통효낭연합불계리진효낭치료만성뇌공혈불족적림상료효。방법장96례만성뇌공혈불족환자안취진순서호수궤분위치료조화대조조,매조46례。치료조여뇌심통효낭연합불계리진효낭종합치료,대조조여불계리진효낭등서약상규치료,련용2개월。관찰2조림상료효,병채용경로다보륵(TCD)검측2조대뇌중동맥(MCA)、추동맥(VA)、기저동맥(BA)적평균혈류속도(Vm)。결과치료조총유효솔위95.65%(44/46),대조조위73.91%(34/46),2조비교차이유통계학의의(P＜0.05)。치료1개월,2조MCA、VA、BA적Vm균교치료전략유증가,단차이무통계학의의(P＞0.05)；치료2개월,치료조환자MCA、VA、BA적Vm균교치료전명현증가(P＜0.05),여대조조비교차이유통계학의의(P＜0.05)。결론뇌심통효낭연합불계리진효낭치료만성뇌공혈불족,재완해증상、개선혈류동역학방면균교단순서약치료유명현우세。
Objective To observe the effects of Naoxintong capsule combined with Fluorine cinnarizine capsules in the treatment of chronic cerebral circulation insufficiency. Methods Totally 92 chronic cerebral circulation insufficiency patients were randomly divided into two groups (46 cases for each). The treatment group was given Naoxintong capsule combined with Fluorine cinnarizine capsules, while the control group was given Fluorine cinnarizine capsules and conservative western medicine treatment. The treatment course was 2 months. The clinical efficacy was observed and Vm of MCA, VA and BA of the two groups was detected by TCD. Results The total effectiveness of treatment group was 95.65% (44/46), the control group was 73.91% (34/46), there was a significant difference (P<0.05). After treated for 1 month, Vm of MCA, VA, BA were increased slightly than those before treatment in both groups (P>0.05). After treated for 2 months, Vm of MCA, VA, BA were significantly increased in treatment group (P<0.05), and had significant difference with that of the control group (P<0.05). Conclusion Compared with the pure western medicine treatment, Naoxintong capsule combined with Fluorine cinnarizine capsules has obvious advantages in alleviating the symptoms and improving hemodynamics in the treatment of chronic cerebral circulation insufficiency.