CAJ | 학술논문

表皮葡萄球菌是一类定植于人体皮肤表面重要的血浆凝固酶阴性葡萄球菌。长期以来，表皮葡萄球菌都被定义为正常菌群，最主要的原因是认为其不能分泌毒素，致病力低。但最近的研究表明，表皮葡萄球菌可通过产生一系列分子来帮助其免受宿主免疫系统的伤害，包括多种蛋白和胞外聚合物。特别是具有溶细胞特性的肽家族-酚可溶性调节蛋白的发现，修正了其不能分泌毒素的观念。
표피포도구균시일류정식우인체피부표면중요적혈장응고매음성포도구균。장기이래，표피포도구균도피정의위정상균군，최주요적원인시인위기불능분비독소，치병력저。단최근적연구표명，표피포도구균가통과산생일계렬분자래방조기면수숙주면역계통적상해，포괄다충단백화포외취합물。특별시구유용세포특성적태가족-분가용성조절단백적발현，수정료기불능분비독소적관념。
Staphylococcus epidermidis is the most important member of the coagulase-negative staphylococci and one of the most abundant colonizers of human skin.S.epidermidis is a bacterial species that is commonly described as relatively innoc-uous,which is in part due to the notion that it lacks secreted toxins with limited capability of infection.S.epidermidis pro-duces a series of molecules that provide protection from host defenses,including many proteins and exopolymers.Further-more,recent research has identified a family of cytolytic peptidesin S.epidermidis,the phenolsoluble modulins (PSMs),and the notion that S.epidermidis is virtually toxin-free had to be somewhat revised.