CAJ | 학술논문

目的：分析55例急性散发性诺如病毒性腹泻患者的流行病学特征和临床特点，为该病的防治提供科学依据。方法收集扬州市三家哨点医院2013年1月～12月门诊腹泻患者大便标本513份，分析临床资料，同时用 RT-PCR方法检测诺如病毒。结果诺如病毒阳性者55例，阳性率10.7％。感染者的年龄与未感染诺如病毒患者比较差异有统计学意义（χ2＝4.27，P＜0.05），而性别、职业、是否为食源性疾病与未感染诺如病毒患者比较差异无统计学意义（χ2＝0.086～3.21，P值均＞0.05）。临床症状的发生诺如病毒感染者更易出现发热（χ2＝4.6，P＜0.05），而其他症状如腹泻次数（≥5次/天）、腹痛、恶心、呕吐等与未感染诺如病毒患者比较差异无统计学意义（χ2＝0.139～3.636，P值均＞0.05）。结论诺如病毒是急性腹泻的常见病原体，发病率较高，单凭临床症状很难与其他腹泻相鉴别，需通过病原学诊断确诊。
목적：분석55례급성산발성낙여병독성복사환자적류행병학특정화림상특점，위해병적방치제공과학의거。방법수집양주시삼가초점의원2013년1월～12월문진복사환자대편표본513빈，분석림상자료，동시용 RT-PCR방법검측낙여병독。결과낙여병독양성자55례，양성솔10.7％。감염자적년령여미감염낙여병독환자비교차이유통계학의의（χ2＝4.27，P＜0.05），이성별、직업、시부위식원성질병여미감염낙여병독환자비교차이무통계학의의（χ2＝0.086～3.21，P치균＞0.05）。림상증상적발생낙여병독감염자경역출현발열（χ2＝4.6，P＜0.05），이기타증상여복사차수（≥5차/천）、복통、악심、구토등여미감염낙여병독환자비교차이무통계학의의（χ2＝0.139～3.636，P치균＞0.05）。결론낙여병독시급성복사적상견병원체，발병솔교고，단빙림상증상흔난여기타복사상감별，수통과병원학진단학진。
Objective To investigate the clinical and epidemiological characteristics in 55 patients with Acute Viral Diarrhea caused by Norovirus.And provide basis for preventing and controlling the spread of the disease.Methods A total of 5 1 3 fe-cal samples of diarrhea cases from 3 surveillance hospitals in 2013 from January to December were collected,analyzed the clinical date and detected Norovirus useing RT-PCR.Results The number of Norovirus positive was 55,positive rate was 10.7%.There were significant differences between Norovirus infection and not infected patients for age (χ2=4.27,P<0.05),then there were no significant differences between Norovirus infection and not infected patients for gender,employ-ment,whether food pathogenic diseases (χ2=0.086~3.21,P>0.05).The clinical symptoms of acute gastroenteritis pa-tients caused by Norovirus infection was fever (χ2=4.6,P<0.05),there were no significant differences for diarrhea (≥5 times/day),bellgache,vomiting,nausea (χ2=0.139~3.636,P>0.05).Conclusion Norovirus is common pathogens of a-cute diarrhoea,which incidence is higher.Clinical symptoms alone is difficult to differentiate with other diarrheaphases.The confirmed diagnosis is depended on the etiology.