CAJ | 학술논문

特殊环境对人体健康形成了挑战，如何在特殊环境保证人体健康具有较为重要的意义。本文针对高温和颗粒物污染两种特殊环境，对其与运动促进健康的国内外研究动态进行综述。运动和高温是胰岛素抵抗非药物干预治疗的主流，PGC-1α是机体通过运动、高温获得诸多益处的关键调控因子，新型激素Irisin可能是运动和高温改善胰岛素抵抗内在机理的重要环节。颗粒物暴露对运动机体运动能力和呼吸系统有一定的负面影响，但系统运动可以抵抗颗粒物染污负面作用，自由基和炎症途径关系系统运动阻碍颗粒物染污的可能机制。
특수배경대인체건강형성료도전，여하재특수배경보증인체건강구유교위중요적의의。본문침대고온화과립물오염량충특수배경，대기여운동촉진건강적국내외연구동태진행종술。운동화고온시이도소저항비약물간예치료적주류，PGC-1α시궤체통과운동、고온획득제다익처적관건조공인자，신형격소Irisin가능시운동화고온개선이도소저항내재궤리적중요배절。과립물폭로대운동궤체운동능력화호흡계통유일정적부면영향，단계통운동가이저항과립물염오부면작용，자유기화염증도경관계계통운동조애과립물염오적가능궤제。
It is important to keep human health in special environment, since the special environment has different effects on health.In this review, we focused on high temperature and air particle matter en-vironment, and health promotion of exercise.Exercise and high temperature are the main non-pharma-cological therapeutic interventions of insulin resistance ( IR) .PGC-1αis key regulatory factor in health promotion of exercise and high temperature.The novel hormone Irisin might be the important pathway through which heat and exercise could have positive function on IR.Air particle matter ( PM) is associat-ed with onset of many respiratory diseases and negative effects of exerciser performance.However, regu-lar exercise plays an important role in improving health of respiratory system and lowering the risk induced by PM.Furthermore, free radicals and inflammatory pathways are included in the possible mechanisms of positive physiological effects induced by exercise in air particle matter environment.