CAJ | 학술논문

作为真核细胞中提供能量并与疾病发生相关的重要细胞器，线粒体对于运动表现出高超的可塑性响应。运动可以促进新生线粒体的生物合成、融合与分裂动态平衡及失去功能的线粒体的自噬清除，从而维持整个线粒体网络的功能，保证细胞的能量供给。本文综述了运动应激对这些过程的调控，从线粒体质量控制角度为运动促进健康及预防疾病的机理提供了合理解释。
작위진핵세포중제공능량병여질병발생상관적중요세포기，선립체대우운동표현출고초적가소성향응。운동가이촉진신생선립체적생물합성、융합여분렬동태평형급실거공능적선립체적자서청제，종이유지정개선립체망락적공능，보증세포적능량공급。본문종술료운동응격대저사과정적조공，종선립체질량공제각도위운동촉진건강급예방질병적궤리제공료합리해석。
Regular exercise has been known to have many benefits, for example, improving physical per-formance, promoting health and preventing chronic diseases such as metabolic diseases.As a very impor-tant organelles in eukaryotic cells, mitochondria exhibit superb plasticity in response to exercise.Exercise may promote mitochondrial biogenesis and eliminate the dysfunctional mitochondria via mitophagy in order to maintain the normal function of the mitochondrial network.These dynamic changes keep mitochondria in health state and ensure the energy supply for cells.This review summarized the studies on the regula-tion of mitochondrial quality control by exercise, and provided a reasonable explanation for exercise to promote health and prevent diseases.