国际检验医学杂志
國際檢驗醫學雜誌
국제검험의학잡지
INTERNATIONAL JOURNAL OF LABORATORY MEDICINE
2014年
13期
1681-1682
,共2页
泌尿系统%真菌%微生物敏感性试验
泌尿繫統%真菌%微生物敏感性試驗
비뇨계통%진균%미생물민감성시험
urinary system%fungus%microbial sensitivity tests
目的:了解临床泌尿系统真菌分布及其药敏情况,指导临床合理使用抗菌药物。方法对2012年1月至2013年6月期间临床送检的泌尿系统标本进行真菌鉴定,并检测其对5种抗菌药物的敏感性,结果采用 WHONET 软件进行统计学分析。结果(1)共分离出真菌239株,其中白色念珠菌居首位,其余依次为光滑念珠菌和热带念珠菌;(2)239株真菌对氟康唑(FCA)、伊曲康唑(ITR)、伏立康唑(VRC)、5-氟胞嘧啶(5-FC)及两性霉素(AMB)的敏感率分别为63.2%、61.9%、92.5%、93.7%及93.7%;(3)白色念珠菌对5种抗菌药物的敏感性较好,均达到95.0%以上;(4)光滑念珠菌对 FCA 和 ITR 的敏感性最低,仅为9.7%。结论泌尿系统真菌感染以白色念珠菌为主,由于各种念珠菌对5种抗真菌药物的敏感性不同,因此加强泌尿系统真菌鉴定及药敏检测,能够为临床合理使用抗菌药物提供重要参考依据。
目的:瞭解臨床泌尿繫統真菌分佈及其藥敏情況,指導臨床閤理使用抗菌藥物。方法對2012年1月至2013年6月期間臨床送檢的泌尿繫統標本進行真菌鑒定,併檢測其對5種抗菌藥物的敏感性,結果採用 WHONET 軟件進行統計學分析。結果(1)共分離齣真菌239株,其中白色唸珠菌居首位,其餘依次為光滑唸珠菌和熱帶唸珠菌;(2)239株真菌對氟康唑(FCA)、伊麯康唑(ITR)、伏立康唑(VRC)、5-氟胞嘧啶(5-FC)及兩性黴素(AMB)的敏感率分彆為63.2%、61.9%、92.5%、93.7%及93.7%;(3)白色唸珠菌對5種抗菌藥物的敏感性較好,均達到95.0%以上;(4)光滑唸珠菌對 FCA 和 ITR 的敏感性最低,僅為9.7%。結論泌尿繫統真菌感染以白色唸珠菌為主,由于各種唸珠菌對5種抗真菌藥物的敏感性不同,因此加彊泌尿繫統真菌鑒定及藥敏檢測,能夠為臨床閤理使用抗菌藥物提供重要參攷依據。
목적:료해림상비뇨계통진균분포급기약민정황,지도림상합리사용항균약물。방법대2012년1월지2013년6월기간림상송검적비뇨계통표본진행진균감정,병검측기대5충항균약물적민감성,결과채용 WHONET 연건진행통계학분석。결과(1)공분리출진균239주,기중백색념주균거수위,기여의차위광활념주균화열대념주균;(2)239주진균대불강서(FCA)、이곡강서(ITR)、복립강서(VRC)、5-불포밀정(5-FC)급량성매소(AMB)적민감솔분별위63.2%、61.9%、92.5%、93.7%급93.7%;(3)백색념주균대5충항균약물적민감성교호,균체도95.0%이상;(4)광활념주균대 FCA 화 ITR 적민감성최저,부위9.7%。결론비뇨계통진균감염이백색념주균위주,유우각충념주균대5충항진균약물적민감성불동,인차가강비뇨계통진균감정급약민검측,능구위림상합리사용항균약물제공중요삼고의거。
Objective To understand the distribution and drug resistance of fungus isolated from urinary tract infection for guid-ing clinical rational drug use.Methods The clinically submitted urinary system samples from January 2012 to June 2013 were per-formed the fungal identification and the drug susceptibility test to 5 kinds of anti-fungal drugs.The detection results were analyzed by the WHONET software.Results (1)239 strains of fungi were isolated,in which Candida albicans occupied the top place,fol-lowed by Candida glabrata and Candida tropicalis;(2)the sensitivity rates of 239 fungal strains to fluconazole(FCA),itraconazole (ITR),voriconazole(VRC),5-fluorocytosine(5-FC)and amphotericin B(AMB)were 63.2%,61.9%,92.5%,93.7% and 93.7%respectively;(3)Candida albicans had the high sensitivity to 5 kinds of anti-fungal drugs,which reached more than 95%;(4)Candida gla-brata had the lowest sensitivity to FCA and ITR,only 9.7%.Conclusion The fungal infection in the urinary system is dominated by Candi-da albicans,due to the different sensitivity to 5 kinds of anti-fungal drugs in different fungi,therefore strengthening the fungal identification of the urinary system and the drug sensitivity test can provide the important reference basis for clinical rational use of anti-fungal drugs.