CAJ | 학술논문

目的观察颌下腺移位术防治鼻咽癌放疗后口干燥症的临床疗效.方法选择符合入选标准的鼻咽癌患者44例,按随机数字表法分成两组,试验组21例,在放疗前将颌下腺移位至颏下区,术后接受常规放疗,放疗时颏下区设置挡块.对照组23例行常规放射治疗.所有病例治疗前均无口干症状且放射剂量相同,放疗后2年进行口干程度问卷调查及分析比较.结果放疗后2年,对照组无口干燥症(G1)0例,轻微干燥症(G2)6例,占26.1%,中度口干燥症(G3)12例,占52.2%,重度口干燥症(G4)5例,占21.7%;试验组无口干燥症(G1)13例,占61.9%,轻微干燥症(G2)6例,占28.6%,中度口干燥症(G3)2例,占9.5%,重度口干燥症(G4)0例;中至重度口干燥症两者之间差异有极显著性(P<0.01).结论颌下腺移位术能明显减轻鼻咽癌患者的口干燥症状,显著改善鼻咽癌患者放疗后的生存质量,且方法简单,值得推广.
목적 관찰합하선이위술방치비인암방료후구간조증적림상료효.방법 선택부합입선표준적비인암환자44례,안수궤수자표법분성량조,시험조21례,재방료전장합하선이위지해하구,술후접수상규방료,방료시해하구설치당괴.대조조23례행상규방사치료.소유병례치료전균무구간증상차방사제량상동,방료후2년진행구간정도문권조사급분석비교.결과 방료후2년,대조조무구간조증(G1)0례,경미간조증(G2)6례,점26.1%,중도구간조증(G3)12례,점52.2%,중도구간조증(G4)5례,점21.7%;시험조무구간조증(G1)13례,점61.9%,경미간조증(G2)6례,점28.6%,중도구간조증(G3)2례,점9.5%,중도구간조증(G4)0례;중지중도구간조증량자지간차이유겁현저성(P<0.01).결론 합하선이위술능명현감경비인암환자적구간조증상,현저개선비인암환자방료후적생존질량,차방법간단,치득추엄.
Objective To observe clinical curative effect of glandula angularis transposition to treat xerostomia because of the postradiotherapy of nasopharyngel carcinoma.Methods 44 standard nasopharyngeal carcinoma patients, were divided into two groups according to the form law of random digit, experimental groups with 21 cases, glandula angularis were shifted the district under the chin jaw before radiotherapy, accepted regular radiotherapy while being postoperative, chin district were setted up block piece when the radiotherapy, control group with 23 cases were accepted the regular radiotherapy. It is the same that all cases did not have a mouth that did symptom and radiated the dosage before treatment, carried on the xerostomia questionnaire investigation of the intensity, analyzed and compared after 2 years radiotherapy. Results Radiotherapy after 2 years, in the control group (G1) there were 0 cases of xerostomia, 6 caseses were slight dries (26.1%) in (G2),12 caseses were intermediate dries month disease (52.2%) in (G3), there were 5 (21.7%) of severe xerostomia in (G4); there were no xerostomia in experimental group, there were 13 eases (61.9%) in (G1), and there were 6 caseses of dries slight(28.6%) in (G2), 2 caseses of intermediate dries (9.5%) in (G3), the number of severe xerostomia is 0 in (G4), Difference has statistics meaning (X2=18.55, P < 0.01) between the two from intermediate to severe xerostomia.Conclusions The glandula angularis transposition can obviously lighten the naspharyngeal carcinoma patients' xerostomia, improve the existenee quality after patients' radiotherapy for nasopharyngeal carcinoma notably, and the method is simple,worth extending.