CAJ | 학술논문

目的：了解黄疸患儿新生儿溶血病（HDN）的发病率，HDN 血型血清学结果与临床诊断符合程度。方法采用微柱凝胶法对276例母婴血型不合的黄疸患儿进行血型血清学3项检测：直接抗球蛋白试验、游离抗体试验及抗体释放试验。结果临床诊断为 HDN 108例，阳性率为39．13％。患儿出生后0～2 d 内阳性检出率最高为50．00％。结论血型血清学试验可为新生儿溶血病的早期诊断、治疗提供依据，尽早采集患儿标本可提高阳性诊断率。
목적：료해황달환인신생인용혈병（HDN）적발병솔，HDN 혈형혈청학결과여림상진단부합정도。방법채용미주응효법대276례모영혈형불합적황달환인진행혈형혈청학3항검측：직접항구단백시험、유리항체시험급항체석방시험。결과림상진단위 HDN 108례，양성솔위39．13％。환인출생후0～2 d 내양성검출솔최고위50．00％。결론혈형혈청학시험가위신생인용혈병적조기진단、치료제공의거，진조채집환인표본가제고양성진단솔。
Objective To understand the incidence of hemolytic disease in newborn (HDN)among the newborns with jaundice and the coincidence degree of the blood group serological results and the clinical diagnosis in HDN.Methods The microcolumn gel method was adopted to detect the 3 serological indexes in 276 jaundice newborns of maternal fetal blood group incompatibility,in-cluding the direct antiglobulin test,free antibody test and antibody release test.Results 108 cases of HDN were clinically diagnosed with the positive rate of 39.13%.The positive detection rate in newborns with 0-2 d old was highest(50.00%).Conclusion The serological test can provide the basis for the early diagnosis and treatment of HDN.Collecting the specimen as early as possible can improve the positive diagnosis rate of HDN.