CAJ | 학술논문

将离子液体（1-丁基-3甲基咪唑六氟磷酸盐，[Bmim ][PF6]）与石墨粉混合，制备了离子液体修饰碳糊电极（CILE），在0.1mol/L N H3-N H4 Cl盐缓冲溶液中（pH9.0），采用循环伏安法（CV ），研究了尼群地平在不同电极上的电化学行为，建立了CILE测定尼群地平的电化学方法．结果表明，在0.1 V/s扫速下，尼群地平的氧化还原峰电位差（ΔEP ）为53mV ．尼群地平的氧化峰电流与其浓度在1.0～200μmol/L范围内呈线性关系（r＝0．9901），检出限为0.3μmol/L （S/N＝3）．该修饰电极成功用于片剂中尼群地平含量的测定，且其电子转移速率、重复性和灵敏度优于传统碳糊电极，但存在较大的背景电流．
장리자액체（1-정기-3갑기미서륙불린산염，[Bmim ][PF6]）여석묵분혼합，제비료리자액체수식탄호전겁（CILE），재0.1mol/L N H3-N H4 Cl염완충용액중（pH9.0），채용순배복안법（CV ），연구료니군지평재불동전겁상적전화학행위，건립료CILE측정니군지평적전화학방법．결과표명，재0.1 V/s소속하，니군지평적양화환원봉전위차（ΔEP ）위53mV ．니군지평적양화봉전류여기농도재1.0～200μmol/L범위내정선성관계（r＝0．9901），검출한위0.3μmol/L （S/N＝3）．해수식전겁성공용우편제중니군지평함량적측정，차기전자전이속솔、중복성화령민도우우전통탄호전겁，단존재교대적배경전류．
An ionic liquid modified carbon paste electrode (CILE) was fabricated by hydrophobic ionic liquid ,1-butyl-3-methyl-imidazolium hexafluorophosphate ([Bmim][PF6 ]) as the binder . Electrochemical behaviors of nitrendipine (NT) were studied at the proposed electrode by cyclic voltammetry (CV) in 0.1mol/L NH3-NH4Cl buffer solution (pH9.0) ,and differential pulse voltammetric determination method was established . The peak-to-peak potential separation (ΔEp ) of paracetamol was 0.053 V with scan rate of 0.1V/s .The results showed that CILE exhibited better electrocatalysis for redox of NT than traditional carbon paste electrode (TCPE) .The oxidation peak current versus concentration of NT at CILE showed linearity in the range of 1.0~200μmol/L(r=0.990 1) with a detection limit of 0.3μmol/L(S/N=3) .The proposed method was applied to determining NT in tablets successfully by differential pulse voltammetry (DPV ) .In terms of electron transfer rate ,reversibility and sensitivity ,CILE is superior to TCPE except for larger background current .