CAJ | 학술논문

目的：恶性肿瘤患者本身存在着凝血和纤维蛋白溶解系统(简称凝溶系统)的异常，加之使用PICC置管，上肢深静脉血栓形成的概率将进一步增加。本研究旨在说明恶性肿瘤患者行PICC穿刺静脉血栓形成与D-2聚体的相关性，为PICC置管患者血栓相关安全性提供一定的参考依据。方法：将本科室所收治的接受 PICC 置管的恶性肿瘤患者进行 D-2聚体检测，对比分析D-2聚体正常与异常情况下，上肢深静脉血栓的发生概率。结果：经统计，两组患者性别及年龄无统计学差异。D-2聚体异常升高组的上肢深静脉血栓发生率明显高于正常组。结论：恶性肿瘤患者D-2聚体的异常升高，在进行PICC置管时，将出现更高的静脉血栓的发生率，此时进行血栓相关干预，可以降低上肢DVT的发生率，提高PICC置管的安全性。
목적：악성종류환자본신존재착응혈화섬유단백용해계통(간칭응용계통)적이상，가지사용PICC치관，상지심정맥혈전형성적개솔장진일보증가。본연구지재설명악성종류환자행PICC천자정맥혈전형성여D-2취체적상관성，위PICC치관환자혈전상관안전성제공일정적삼고의거。방법：장본과실소수치적접수 PICC 치관적악성종류환자진행 D-2취체검측，대비분석D-2취체정상여이상정황하，상지심정맥혈전적발생개솔。결과：경통계，량조환자성별급년령무통계학차이。D-2취체이상승고조적상지심정맥혈전발생솔명현고우정상조。결론：악성종류환자D-2취체적이상승고，재진행PICC치관시，장출현경고적정맥혈전적발생솔，차시진행혈전상관간예，가이강저상지DVT적발생솔，제고PICC치관적안전성。
Objective:The rate of DVT in upper limb will increase in malignant cancer patients, because of the abnormal with Coagulation and Fibrinolysis System (CFS), in addition to the use of PICC.In order to describe the correlation of DVT in malignant cancer patients with PICC and D-dimmer in order to provide the evidence for the safety of patients with PICC.Methods:All the cancer patients with PICC will be inspected the D-dimmer and compared with the rate of DVT in normal and abnormal of the D-dimmer.Results:There is no significant difference in age and sexuality of the two groups. The incidence of abnormal elevation group was significantly higher than that of the normal group.Conclusion: When the D-dimmer is significantly high in malignant cancer patients accepting the PICC, there would be significantly higher incidence of the DVT in upper limb. Intervention to the thrombus can be done to decrease the incidence of DVT and raise the safety of the PICC.