CAJ | 학술논문

目的：探讨肝细胞癌( HCC)肝外转移最常见的部位及对患者生存预后的影响。方法收集经PET/CT检查确诊HCC肝外转移的病例132例,对其HCC转移部位进行回顾性分析,同时行单因素、多因素生存分析。结果 HCC 肝外转移最常见的部位是淋巴结(54.5%,72/132)、骨(24.2%,32/132)和肺(21.2%,28/132)；单因素和多因素生存分析均提示淋巴结转移对患者生存预后有显著影响(P值均<0.05),而其他转移部位和生理指标对生存预后均无显著影响(P值均>0.05)。结论淋巴结转移在HCC肝外转移最常见且可显著影响患者生存预后,及早诊断及治疗淋巴结转移病灶将能改善患者生存质量,延长生存时间。
목적：탐토간세포암( HCC)간외전이최상견적부위급대환자생존예후적영향。방법수집경PET/CT검사학진HCC간외전이적병례132례,대기HCC전이부위진행회고성분석,동시행단인소、다인소생존분석。결과 HCC 간외전이최상견적부위시림파결(54.5%,72/132)、골(24.2%,32/132)화폐(21.2%,28/132)；단인소화다인소생존분석균제시림파결전이대환자생존예후유현저영향(P치균<0.05),이기타전이부위화생리지표대생존예후균무현저영향(P치균>0.05)。결론림파결전이재HCC간외전이최상견차가현저영향환자생존예후,급조진단급치료림파결전이병조장능개선환자생존질량,연장생존시간。
Objective To investigate the most common sites and the impact of survival prognosis for patients in the extrahepatic metastasis of liver cancer. Methods One hundred and thirty-two cases confirmed with HCC extrahepatic metastasis by PET/CT examination were collected in our department. These cases were retrospectively analyzed, univariate and multivariate survival analysis were conducted. Results The most common sites of HCC extrahepatic metastasis were lymph nodes (54. 5%,72/132), bone (24. 2%, 32/132) and lung (21. 2%, 28/132), the univariate and multivariate survival analysis prompted to lymph node metastasis had a significant effect on survival prognosis (all P values <0. 05), while other transfer locus and physiological indices had no significant effects (all P values > 0. 05). Conclusions Lymph node metastasis in HCC extrahepatic metastasis is the most common and can significantly affect patients survival prognosis. Early diagnosis and treatment of lymph node metastasis in patients will be able to improve the quality of survival and prolong the survival time.