国际儿科学杂志
國際兒科學雜誌
국제인과학잡지
INTERNATIONAL JOURNAL OF PEDIATRICS
2013年
1期
80-83
,共4页
CD40-CD40配体%儿科疾病
CD40-CD40配體%兒科疾病
CD40-CD40배체%인과질병
CD40-CD40 ligand%Pediatric disease
CD40-CD40配体(CD40-CD40L)交联是体内免疫反应中一条重要的细胞信号传导通路,参与细胞免疫和体液免疫调节.CD40-CD40L信号传导通路异常可导致机体免疫系统发生紊乱,产生免疫病理反应.儿科多种疾病如免疫缺陷病、某些炎症性疾病和免疫性疾病的发生与CD40-CD40L信号传导通路异常有密切关系.研究CD40-CD40L与这些疾病之间的关系具有重要的临床意义.
CD40-CD40配體(CD40-CD40L)交聯是體內免疫反應中一條重要的細胞信號傳導通路,參與細胞免疫和體液免疫調節.CD40-CD40L信號傳導通路異常可導緻機體免疫繫統髮生紊亂,產生免疫病理反應.兒科多種疾病如免疫缺陷病、某些炎癥性疾病和免疫性疾病的髮生與CD40-CD40L信號傳導通路異常有密切關繫.研究CD40-CD40L與這些疾病之間的關繫具有重要的臨床意義.
CD40-CD40배체(CD40-CD40L)교련시체내면역반응중일조중요적세포신호전도통로,삼여세포면역화체액면역조절.CD40-CD40L신호전도통로이상가도치궤체면역계통발생문란,산생면역병리반응.인과다충질병여면역결함병、모사염증성질병화면역성질병적발생여CD40-CD40L신호전도통로이상유밀절관계.연구CD40-CD40L여저사질병지간적관계구유중요적림상의의.
CD40-CD40 ligand (CD40-CD40L) cross-linking,an important cell signaling transduction pathway in immune response,is involved in the regulation of cellular and humoral immune.CD40-CD40L signaling pathway abnormalities can lead to immune system disorders and incur immune pathological reaction.A variety of common pediatric diseases,such as immunodeficiency diseases,inflammatory diseases and autoimmune diseases,are associated with CD40-CD40L signaling transduction pathway abnormalities.The relationship between CD40-CD40L and the above-mentioned diseases is of clinical significance.
