功能材料
功能材料
공능재료
JOURNAL OF FUNCTIONAL MATERIALS
2014年
8期
8007-8012
,共6页
壳聚糖水凝胶%质构关系%温敏可逆相变%无酶处理%液体栓塞
殼聚糖水凝膠%質構關繫%溫敏可逆相變%無酶處理%液體栓塞
각취당수응효%질구관계%온민가역상변%무매처리%액체전새
chitosan hydrogel%ingredient-structure correlation%thermo-reversible phase transition%non-enzyme cell harvest%fluid embolizing agents
壳聚糖温敏水凝胶是一种非化学交联智能水凝胶,其成胶性能取决于凝胶组分,形成特定的质-构关系。温和的制备条件和良好的生物活性,使壳聚糖水凝胶在组织工程、药物缓释,特别是细胞培养、液态栓塞剂等领域的研究应用取得了新进展。综述了壳聚糖温敏水凝胶的分类、成胶性能、相变机制及其在生物医药领域研究和应用的新进展。
殼聚糖溫敏水凝膠是一種非化學交聯智能水凝膠,其成膠性能取決于凝膠組分,形成特定的質-構關繫。溫和的製備條件和良好的生物活性,使殼聚糖水凝膠在組織工程、藥物緩釋,特彆是細胞培養、液態栓塞劑等領域的研究應用取得瞭新進展。綜述瞭殼聚糖溫敏水凝膠的分類、成膠性能、相變機製及其在生物醫藥領域研究和應用的新進展。
각취당온민수응효시일충비화학교련지능수응효,기성효성능취결우응효조분,형성특정적질-구관계。온화적제비조건화량호적생물활성,사각취당수응효재조직공정、약물완석,특별시세포배양、액태전새제등영역적연구응용취득료신진전。종술료각취당온민수응효적분류、성효성능、상변궤제급기재생물의약영역연구화응용적신진전。
Chitosan based thermosensitive hydrogel was a type of intelligent gel that was nonchemical-crosslinked,whose structures are closely correlated with specific ingredients.Its mild preparation,desirable bioactivity and biocompatibility make it broadly applied in tissue engineering and drug controlled release.Nota-bly,its applications as fluid embolizing agent and cell culture matrix for ready harvest have attracted numerous attentions recently.This review intends to summarize its categorization,gelling behavior,mode of gelation and novel applications.