CAJ | 학술논문

目的：观察神经复原方联合阿司匹林预防缺血性脑卒中复发的临床疗效。方法将100例缺血性脑卒中患者按随机数字表法分为治疗组和对照组，各50例。在基础治疗的同时，治疗组口服神经复原方和阿司匹林，对照组口服辛伐他汀和阿司匹林，3个月为1个疗程。每隔3个月服1个疗程，共服4个疗程。结果治疗组脑梗死复发率为6％，对照组为12％，两组比较差异无统计学意义（ P ＞0．05）；但缺血性事件（包括脑梗死及短暂性脑缺血发作）发生率，两组比较差异有统计学意义（12％ vs 28％，P ＜0．05）。治疗组治疗后6个月、12个月和24个月时血小板聚集率低于对照组，差异有统计学意义（ P ＜0．05），但低密度脂蛋白胆固醇与对照组比较差异无统计学意义。结论神经复原方联合阿司匹林可以降低缺血性事件的发生。
목적：관찰신경복원방연합아사필림예방결혈성뇌졸중복발적림상료효。방법장100례결혈성뇌졸중환자안수궤수자표법분위치료조화대조조，각50례。재기출치료적동시，치료조구복신경복원방화아사필림，대조조구복신벌타정화아사필림，3개월위1개료정。매격3개월복1개료정，공복4개료정。결과치료조뇌경사복발솔위6％，대조조위12％，량조비교차이무통계학의의（ P ＞0．05）；단결혈성사건（포괄뇌경사급단잠성뇌결혈발작）발생솔，량조비교차이유통계학의의（12％ vs 28％，P ＜0．05）。치료조치료후6개월、12개월화24개월시혈소판취집솔저우대조조，차이유통계학의의（ P ＜0．05），단저밀도지단백담고순여대조조비교차이무통계학의의。결론신경복원방연합아사필림가이강저결혈성사건적발생。
O bjective To observe the effect of Shenjing Fuyuan decoction (SFD) plus aspirin on preventing the recurrence of is-chem ic stroke .M ethods O ne hundred patients w ith ischem ic stroke w ere random ly divided into tw o groups :Treatm ent group ( n =50) treated by oralSFD plus aspirin ,and contro lgroup ( n = 50) treated by sim vastatin plus aspirin on the basis of routine treatm ent. Three m onths w as a course of treatm ent.Results The recurrence rate of cerebral infarction w as 6% in treatm ent group and 12% in contro l group ( P > 0.05) .The incidence rate of ischem ic events including cerebral infarction and transient ischem ic attack(TIA) w as 12% in treatm ent group ,w hich w as low er than that in contro l group ( 28% ,P < 0.05) .The decrease of platelet aggregation rate in 6 m onths ,12 m onths and 24 m onths in treatm ent group was better than that in contro l group ( P < 0.05) .There was no significant differ-ence in the low density lipoprotein cholesterolbetw een two groups.Conclusion SFD plus aspirin could reduce the incidence of ischem ic events.