CAJ | 학술논문

目的：探索老老年原发性高血压患者昼夜血压节律与平均血小板体积（M PV）的相关性。方法选择中国中医科学院广安门医院2013年8月-2014年1月心内科住院高血压患者100例，根据血压昼夜节律的不同，将患者分为3组：杓型组24例，非杓型组26例，反杓型组50例。比较3组间平均血小板体积及分析其影响因素。结果3组间 M PV 值比较，杓型组＜非杓型组＜反杓型组，差异有统计学意义（ P ＜0．01）。 M PV与夜间血压下降率存在显著相关性（ r＝-0．299，P ＝0．035）；M PV与 ALT、AST均呈正相关性，与 HDL C呈负相关。结论在老老年高血压患者的血压昼夜节律于 M PV之间关系密切，在临床诊疗中，应重视 M PV的监测，调节血压昼夜节律，改善患者自主神经功能，提前进行干预，从而减少急性血栓事件的发生，改善心脑血管病预后。
목적：탐색로노년원발성고혈압환자주야혈압절률여평균혈소판체적（M PV）적상관성。방법선택중국중의과학원엄안문의원2013년8월-2014년1월심내과주원고혈압환자100례，근거혈압주야절률적불동，장환자분위3조：표형조24례，비표형조26례，반표형조50례。비교3조간평균혈소판체적급분석기영향인소。결과3조간 M PV 치비교，표형조＜비표형조＜반표형조，차이유통계학의의（ P ＜0．01）。 M PV여야간혈압하강솔존재현저상관성（ r＝-0．299，P ＝0．035）；M PV여 ALT、AST균정정상관성，여 HDL C정부상관。결론재로노년고혈압환자적혈압주야절률우 M PV지간관계밀절，재림상진료중，응중시 M PV적감측，조절혈압주야절률，개선환자자주신경공능，제전진행간예，종이감소급성혈전사건적발생，개선심뇌혈관병예후。
O bjective To explo re the very elderly pa tients w ith essential hypertension circadian rhythm of blood pressure and m ean platelet vo lum e corre lation.M ethods G uang’ anm en Hospital,China Academ y ofC hineseM edicalS cience from August 2013 to January 2014 C ardio logy hospitalized 100 patients w ith hypertension w ere included.D epending on the circadian rhythm , the patients w ere divided into three groups :D ippers group( n= 24) ,non dipper group( n= 26) ,anti dipper group( n= 50) .C om parison Am ong the three groups m ean platelet vo lum e and analyze its influencing factors .Results There w as difference in M PV value com pari-son am ong three g roups( P < 0.01) , and dipper group < non dipper group < anti dipper group .There w as a correlation betw een MVP and the decline rate of nocturnal blood pressure( r= - 0.299,P = 0.035) .There w as a positive correlation be tw een MVP and ALT ,AST .There w as a negative correlation betw eenMVP and HDL C .Conclusion In very elderly hypertensive pa tients in the close relationship betw een circadian rhythm and M PV , in clinica l practice , should pay attention M PV m onito ring , regulating circadian rhythm s , im proving autonom ic function in patients , early intervention , thereby reducing the tim e of acute throm bosis occurred , im-proving the prognosis of cardiovascular disease .