CAJ | 학술논문

目的：观察血液透析联合血液灌流治疗尿毒症患者皮肤瘙痒的疗效。方法：将2012年2月～2014年1月间在本院进行维持性血液透析并出现皮肤瘙痒的80例尿毒症患者随机分为治疗组（n=40）和对照组（n=40），治疗组患者采用血液透析联合血液灌流治疗，对照组患者给予血液透析治疗。结果：治疗组患者的皮肤瘙痒症状明显改善，血β2微球蛋白（β2-MG）、甲状旁腺激素（PTH）、血肌酐（Scr）和尿素氮（BUN）均显著低于对照组患者（P<0.05），但是两组患者之间的血钙没有显著差异（P>0.05）。结论：血液透析联合血液灌流可以显著改善尿毒症患者的皮肤瘙痒，值得在临床推广应用。
목적：관찰혈액투석연합혈액관류치료뇨독증환자피부소양적료효。방법：장2012년2월～2014년1월간재본원진행유지성혈액투석병출현피부소양적80례뇨독증환자수궤분위치료조（n=40）화대조조（n=40），치료조환자채용혈액투석연합혈액관류치료，대조조환자급여혈액투석치료。결과：치료조환자적피부소양증상명현개선，혈β2미구단백（β2-MG）、갑상방선격소（PTH）、혈기항（Scr）화뇨소담（BUN）균현저저우대조조환자（P<0.05），단시량조환자지간적혈개몰유현저차이（P>0.05）。결론：혈액투석연합혈액관류가이현저개선뇨독증환자적피부소양，치득재림상추엄응용。
Objective:To observe the effects of hematodialysis and hemoperfusion on skin itch in patients with uremia. Methods:80 patients with uremia undergoing hemodialysis in Blood Purfication Center of SubeiPeoples's Hospital from February 2012 to January 2014 were randomly divided into treatment group(n=40) and control group(n=40).Treatment group was given hematodialysis and hemoperfusion therapy and control group was given hematodialysis therapy. Results: The treatment group patients with itchy skin symptoms improved significantly. Theβ2-MG, PTH, Scr, BUN level of the treatment group were significantly lower than those of the control group(P<0.05).However,there was no significant difference in Ca2+ between two groups(P>0.05). Conclusions:The hematodialysis and hemoperfusion in treatment with skin itch has a better effect,which can be used preferred method to treat skin itch with uremia.