CAJ | 학술논문

目的：探讨换血疗法对新生儿重症高胆红素血症的治疗效果。方法：监测112例新生儿重症高胆红素血症患儿换血前后的胆红素、血常规及电解质指标的变化。结果：换血治疗前后患儿血清总胆红素水平下降59.47%，红细胞压积及血红蛋白上升(P<0.05)，血小板、白细胞计数及血钾下降(P<0.05)，血钠和血钙水平明显增高(P<0.05)。结论：新生儿重症高胆红素血症患儿进行换血治疗可以有效降低体内胆红素水平，对患儿血液内环境有一定影响。
목적：탐토환혈요법대신생인중증고담홍소혈증적치료효과。방법：감측112례신생인중증고담홍소혈증환인환혈전후적담홍소、혈상규급전해질지표적변화。결과：환혈치료전후환인혈청총담홍소수평하강59.47%，홍세포압적급혈홍단백상승(P<0.05)，혈소판、백세포계수급혈갑하강(P<0.05)，혈납화혈개수평명현증고(P<0.05)。결론：신생인중증고담홍소혈증환인진행환혈치료가이유효강저체내담홍소수평，대환인혈액내배경유일정영향。
Objective To explore the curative effect of exchange transfusion for severe neonate hyperbilirubinemia.Methods In 112 severe hyperbilirubinemia of neonates who were performed exchange transfusion, bilirubin, results of blood routine test and electrolyte were detected before and after exchange transfusion.Results After exchange transfusion, the level of total bilirubin in 112 severe hyperbilirubinemia of neonates decreased by 59.47%. HTC and hemoglobin increased(P<0.05). The levels of platelet and white blood cellcount and serum kalium decreased significntly(P<0.05). The levels of serum natrium and serum calcium increased significntly(P<0.05).Conclusion The level of serum bilirubin in neonates with severe neonate hyperbilirubinemia could be decreased effectively by exchange transfusion,which would have certain effects on the internal environment of neonates.