医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2014年
21期
387-388
,共2页
孙小英%奚柏剑%周小萍%徐美云
孫小英%奚柏劍%週小萍%徐美雲
손소영%해백검%주소평%서미운
曲马多%术后%镇痛%效果%安全性%疼痛缓解时间%疼痛程度
麯馬多%術後%鎮痛%效果%安全性%疼痛緩解時間%疼痛程度
곡마다%술후%진통%효과%안전성%동통완해시간%동통정도
tramadol%postoperative%analgesia%effect%safety%the time of pain relief%the degree of pain
目的:探讨曲马多用于术后镇痛的效果及安全性。方法:我院自2012年2月至2013年2月收治腹部手术患者84例,随机分为A、B、C三组,每组各28例,A组患者术后不给予曲马多镇痛,B组患者术后采用硬膜外腔给予曲马多镇痛,C组患者术后静脉给予曲马多镇痛。观察三组患者呼吸系统和循环系统情况,统计三组患者疼痛评分及副作用,评价曲马多镇痛的安全性。结果:呼吸系统和循环系统情况:平均动脉压、心率、呼吸频率无明显变化;在疼痛评分中,A组患者疼痛缓解时间最慢,且疼痛程度也最重,与B组和C组患者相比较,差异性具有统计学意义( P<0.05),疼痛程度和疼痛缓解时间在B组和C组患者之间相比较,差异性不具有统计学意义( P>0.05);主要出现了头晕、呕吐及恶心等副作用,最严重的是A组患者,但是与B组和C组患者相比较,差异性不具有统计学意义( P>0.05)。结论:曲马多用于术后镇痛效果显著,能够明显减轻疼痛的程度及减少疼痛缓解的时间,术后应用曲马多不会影响呼吸系统和循环系统,采用静脉和硬膜外腔给予曲马多镇痛具有基本相同的镇痛效果,且术后给予曲马多可使得呕吐恶心等副作用得到减轻。
目的:探討麯馬多用于術後鎮痛的效果及安全性。方法:我院自2012年2月至2013年2月收治腹部手術患者84例,隨機分為A、B、C三組,每組各28例,A組患者術後不給予麯馬多鎮痛,B組患者術後採用硬膜外腔給予麯馬多鎮痛,C組患者術後靜脈給予麯馬多鎮痛。觀察三組患者呼吸繫統和循環繫統情況,統計三組患者疼痛評分及副作用,評價麯馬多鎮痛的安全性。結果:呼吸繫統和循環繫統情況:平均動脈壓、心率、呼吸頻率無明顯變化;在疼痛評分中,A組患者疼痛緩解時間最慢,且疼痛程度也最重,與B組和C組患者相比較,差異性具有統計學意義( P<0.05),疼痛程度和疼痛緩解時間在B組和C組患者之間相比較,差異性不具有統計學意義( P>0.05);主要齣現瞭頭暈、嘔吐及噁心等副作用,最嚴重的是A組患者,但是與B組和C組患者相比較,差異性不具有統計學意義( P>0.05)。結論:麯馬多用于術後鎮痛效果顯著,能夠明顯減輕疼痛的程度及減少疼痛緩解的時間,術後應用麯馬多不會影響呼吸繫統和循環繫統,採用靜脈和硬膜外腔給予麯馬多鎮痛具有基本相同的鎮痛效果,且術後給予麯馬多可使得嘔吐噁心等副作用得到減輕。
목적:탐토곡마다용우술후진통적효과급안전성。방법:아원자2012년2월지2013년2월수치복부수술환자84례,수궤분위A、B、C삼조,매조각28례,A조환자술후불급여곡마다진통,B조환자술후채용경막외강급여곡마다진통,C조환자술후정맥급여곡마다진통。관찰삼조환자호흡계통화순배계통정황,통계삼조환자동통평분급부작용,평개곡마다진통적안전성。결과:호흡계통화순배계통정황:평균동맥압、심솔、호흡빈솔무명현변화;재동통평분중,A조환자동통완해시간최만,차동통정도야최중,여B조화C조환자상비교,차이성구유통계학의의( P<0.05),동통정도화동통완해시간재B조화C조환자지간상비교,차이성불구유통계학의의( P>0.05);주요출현료두훈、구토급악심등부작용,최엄중적시A조환자,단시여B조화C조환자상비교,차이성불구유통계학의의( P>0.05)。결론:곡마다용우술후진통효과현저,능구명현감경동통적정도급감소동통완해적시간,술후응용곡마다불회영향호흡계통화순배계통,채용정맥화경막외강급여곡마다진통구유기본상동적진통효과,차술후급여곡마다가사득구토악심등부작용득도감경。
Objective:To investigate the effect of tramadol analgesia effect and safety of postoperative.Method:84 cases in our hospital from 2012 February to 2013 February were abdominal operation patients,randomly divided into A,B,C three groups,28 cases in each group,not given tramadol A group patients,B groups of patients with postoperative epidural analgesia with tramadol,group C patients after intravenous.Tramadol analgesia.Observe three groups of patients with respiratory system and circulatory system,three patients pain score and side effects,safety evaluation of tramadol analgesia.Results:the respiratory system and the circulatory system:the mean arterial pressure,heart rate,respiratory rate had no significant change;in pain score in group A,patients with pain relief time most slowly,and the degree of pain is the most important,compared with B group and C group of patients, with statisticaly significant difference (P<0.05),pain and the degree of pain relief time comparison between B group and C group, the difference was not statisticaly significant (P>0.05); mainly appeared dizziness,vomiting and nausea and other side effects,the most serious is the patients in the A group,but compared with B group and C group,the difference was not statisticaly significance (P>0.05).Conclusion: tramadol for postoperative analgesia effect significantly,can significantly reduce the degree of pain and decrease the time of pain relief,tramadol wil not affect the respiratory system and the circulatory system after operation,intravenous and epidural analgesia with tramadol analgesia effect of basicaly the same,and postoperative tramadol can cause side effects such as nausea and vomiting are reduce.