CAJ | 학술논문

目的：探讨磺胺嘧啶银联合卡泊芬净治疗烧伤创面临床疗效。方法80例符合纳入标准的烧伤患者随机分为两组,每组40例。对照组给予卡泊芬净治疗,观察组在对照组的基础上联合使用磺胺嘧啶银治疗。结果观察组抗真菌感染治疗有效率为90.0%,明显高于对照组70.0%的治疗有效率(P<0.05)。观察组浅II度创面和深II度创面愈合时间分别为(8.5±2.9)d和(17.4±4.2)d,明显短于对照组的(11.9±2.5)d和(22.0±4.9)d(P<0.05)。两组患者均未出现严重的不良反应。结论磺胺嘧啶银联合卡泊芬净治疗烧伤创面疗效可靠,可以提高抗真菌感染的治疗有效率,缩短创面愈合时间,不良反应少,值得临床推广。
목적：탐토광알밀정은연합잡박분정치료소상창면림상료효。방법80례부합납입표준적소상환자수궤분위량조,매조40례。대조조급여잡박분정치료,관찰조재대조조적기출상연합사용광알밀정은치료。결과관찰조항진균감염치료유효솔위90.0%,명현고우대조조70.0%적치료유효솔(P<0.05)。관찰조천II도창면화심II도창면유합시간분별위(8.5±2.9)d화(17.4±4.2)d,명현단우대조조적(11.9±2.5)d화(22.0±4.9)d(P<0.05)。량조환자균미출현엄중적불량반응。결론광알밀정은연합잡박분정치료소상창면료효가고,가이제고항진균감염적치료유효솔,축단창면유합시간,불량반응소,치득림상추엄。
Objective To investigate the clinical effect of sulfadiazine silver in combination with caspofungin in the treatment of burn wound.Methods A total of 80 cases of burn patients meeting the inclusion criterions were randomly divided into two groups, and each group contained 40 cases. The control group was treated with caspofungin, and the observation group was treated with additional sulfadiazine silver.Results The observation group had a total anti-fungal infection efficiency rate of 90.0%, which was statistically higher than 70.0% of the control group (P<0.05). The wound healing time of the superficial and deep second-degree burns in the observation group were (8.5±2.9) d and (17.4±4.2) d, which was respectively obviously shorter than (11.9±2.5) d and (22.0±4.9) d of the control group (P<0.05). There were no severe adverse reactions in the two groups.Conclusion Sulfadiazine silver in combination with caspofungin has a reliable curative effect in the treatment of burn wound, which can increase efficiency rate of anti-fungal infection, and shorten wound healing time with few adverse reactions.